PDISの謝辞の入っている論文一覧
 
＊創薬PF事業においては、全国のライフサイエンス研究者の支援に力を入れております。また、支援に供与できる技術開発も行っています。我々の支援先の研究者の論文にPDISの謝辞（This work was supported in part by the Platform for Drug Discovery, Informatics, and Structural Life Science (PDIS) from the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan）を入れて頂いた研究内容についても一緒に紹介します。
 
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76. Maekawa N, Konnai S, Takagi S, Kagawa Y, Okagawa T, Nishimori A, Ikebuchi R, Izumi Y, Deguchi T, Nakajima C, Kato Y, Yamamoto K, Uemura H, Suzuki Y, Murata S, Ohashi K.

A canine chimeric monoclonal antibody targeting PD-L1 and its clinical efficacy in canine oral malignant melanoma or undifferentiated sarcoma.

Sci Rep. ,7(1):8951. doi: 10.1038/s41598-017-09444-2, 2017
 
PDIS
 
75. Itai S, Fujii Y, Nakamura T, Chang YW, Yanaka M, Saidoh N, Handa S, Suzuki H, Harada H, Yamada S, Kaneko MK, Kato Y.
(*corresponding author)

Establishment of CMab-43, a Sensitive and Specific Anti-CD133 Monoclonal Antibody, for Immunohistochemistry.

Monoclon. Antib. Immunodiagn. Immunother., in press
 
PDIS
 
74. Itai S, Kaneko MK, Fujii Y, Yamada S, Nakamura T, Yanaka M, Saidoh N, Handa S, Chang Yao-Wen, Suzuki H, Harada H, Kato Y.
(*corresponding author)

Development of EMab-51, a Sensitive and Specific Anti-EGFR Monoclonal Antibody in Western Blot and Immunohistochemistry.

Monoclon. Antib. Immunodiagn. Immunother., in press
 
PDIS
 
73. Itai S, Yamada S, Kaneko MK, Harada H, Kato Y.
(*corresponding author)

Immunohistochemical Analysis Using Anti-Podocalyxin Monoclonal Antibody PcMab-47 Demonstrates Podocalyxin Expression in Oral Squamous Cell Carcinoma Cells.

Monoclon. Antib. Immunodiagn. Immunother., in press
 
PDIS
 
 
72. Jung E, Gardner D, Choi D, Park E, Jin Seong Y, Yang S, Castorena-Gonzalez J, Louveau A, Zhou Z, Lee GK, Perrault DP, Lee S, Johnson M, Daghlian G, Lee M, Jin Hong Y, Kato Y, Kipnis J, Davis MJ, Wong AK, Hong YK.

Development and Characterization of A Novel Prox1-EGFP Lymphatic and Schlemm's Canal Reporter Rat.

Sci Rep., 7(1):5577. doi: 10.1038/s41598-017-06031-3., 2017
 
PDIS
 
71. Yamada S, Itai S, Nakamura T, Yanaka M, Saidoh N, Chang YW, Handa S, Harada H, Kagawa Y, Ichii O, Konnai S, Kaneko MK, Kato Y.

PMab-52: Specific and Sensitive Monoclonal Antibody against Cat Podoplanin for Immunohistochemistry.

Monoclon. Antib. Immunodiagn. Immunother., in press

PDIS
 
70. Itai S, Fujii Y, Kaneko MK, Yamada S, Nakamura T, Yanaka M, Saidoh N, Chang YW, Handa S, Takahashi M, Suzuki H, Harada H, Kato Y.

H2Mab-77 is a sensitive and specific anti-HER2 monoclonal antibody against breast cancer.

Monoclon. Antib. Immunodiagn. Immunother.,36(4): 143-148, 2017
PDIS
 
69. Okagawa T, Konnai S, Nishimori A, Maekawa N, Ikebuchi R, Goto S, Nakajima C, Kohara J, Ogasawara S, Kato Y, Suzuki Y, Murata S, and Ohashi K.

Anti-Bovine PD-1 Rat-Bovine Chimeric Antibody for Immunotherapy of Bovine Leukemia Virus Infection in Cattle .

Frontiers in Immunology, https://doi.org/10.3389/fimmu.2017.00650., 2017
 
PDIS
 
68. Nakano T, Ogasawara S, Tanaka T, Hozumi Y, Mizuno S, Satoh E, Sakane F, Okada N, Taketomi A, Honma R, Nakamura T, Saidoh N, Yanaka M, Itai S, Handa S, Chang YW, Yamada S, Kaneko MK, Kato Y, Goto K.

DaMab-2: Anti-Human DGK Monoclonal Antibody for immunocytochemistry.

Monoclon. Antib. Immunodiagn. Immunother., 36(4): 181-184, 2017 (PDF)
 
PDIS
 
67. Goto S, Konnai S, Okagawa T, Nishimori A, Maekawa N, Gondaira S, Higuchi H, Koiwa M, Tajima M, Kohara J, Ogasawara S, Kato Y, Suzuki Y, Murata S, Ohashi K.

Increase of cells expressing PD-1 and PD-L1 and enhancement of IFN-γ production via PD-1/PD-L1 blockade in bovine mycoplasmosis.

Immun Inflamm Dis. 2017 May 24. doi: 10.1002/iid3.173. [Epub ahead of print]
 
PDIS
 
66. Nipawan Nuemket, Norihisa Yasui, Yuko Kusakabe, Yukiyo Nomura, Nanako Atsumi, Shuji Akiyama, Eriko Nango, Yukinari Kato, Mika K. Kaneko, Junichi Takagi, Maiko Hosotani & Atsuko Yamashita

Structural basis for perception of diverse chemical substances by T1r taste receptors.

Nature Communications, 8, Article number: 15530, 2017, doi:10.1038/ncomms15530
 
PDIS
 
65. Kaneko MK, Kunita A, Yamada S, Nakamura T, Yanaka M, Saidoh N, Chang YW, Handa S, Ogasawara S, Ohishi T, Abe S, Itai S, Harada H, Kawada M, Nishioka Y, Fukayama M, Kato Y.*
Anti-Podocalyxin Antibody chPcMab-47 Exerts Antitumor Activity in Mouse Xenograft Models of Colorectal Adenocarcinomas.
Monoclon. Antib. Immunodiagn. Immunother., 36(4): 157-162, 2017
 
PDIS
 
64. Asami Nishimori, Satoru Konnai, Tomohiro Okagawa, Naoya Maekawa, Ryoyo Ikebuchi, Shinya Goto, Yamato Sajiki, Yasuhiko Suzuki, Junko Kohara, Satoshi Ogasawara, Yukinari Kato, Shiro Murata, Kazuhiko Ohashi

In vitro and in vivo antivirus activity of an antiprogrammed death-ligand 1 (PD-L1) ratbovine chimeric antibody against bovine leukemia virus infection.

PLoS ONE 12(4): e0174916.
 
PDIS
 
63. Yamada S, Honma R, Kaneko MK, Nakamura T, Yanaka M, Saidoh N, Takagi M, Konnai S, Kato Y.*
(*corresponding author)

Characterization of Anti-bovine Podoplanin Monoclonal Antibody PMab-44

Monoclon. Antib. Immunodiagn. Immunother.,36(3): 129-134, 2017
PDIS
 
62. Shirakabe K, Omura T, Shibagaki Y, Mihara E, Homma K, Kato Y, Yoshimura A, Murakami Y, Takagi J, Hattori S, Ogawa Y.

Mechanistic insights into ectodomain shedding: susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation.

Sci Rep., 7:46174, doi: 10.1038/srep46174, 2017
PDIS
 
61. Kaneko MK, Nakamura T, Kunita A, Fukayama M, Abe S, Nishioka Y, Yamada S, Yanaka M, Saidoh N, Yoshida K, Fujii Y, Ogasawara S, Kato Y.*
(*corresponding author)

ChLpMab-23: Cancer-specific Human-Mouse Chimeric Anti-podoplanin Antibody Exhibits Antitumor Activity via Antibody-Dependent Cellular Cytotoxicity

Monoclon. Antib. Immunodiagn. Immunother., 36(3): 104-112, 2017
PDIS
 
60. Ogasawara S, Kaneko MK, Yamada S, Honma R, Nakamura T, Saidoh N, Yanaka M, Yoshida K, Fujii Y, Kato Y.*

PcMab-47: Novel Anti-human Podocalyxin Monoclonal Antibody for Immunohistochemistry

Monoclon. Antib. Immunodiagn. Immunother., 36(2): 50-56, 2017
PDIS
 
 
59. Yamada S, Ogasawara S, Kaneko MK, Kato Y.*
(*corresponding author)

LpMab-23: A Cancer-Specific Monoclonal Antibody against Human Podoplanin

Monoclon. Antib. Immunodiagn. Immunother., 36(2): 72-76, 2017
 
PDIS
 
58. Yamada S, Kaneko MK, Nakamura T, Ichii O, Konnai S, Kato Y.*
(*corresponding author)
Development of mPMab-1, a Mouse-Rat Chimeric Antibody against Mouse Podoplanin

Monoclon. Antib. Immunodiagn. Immunother., 36(2): 77-79, 2017
 
PDIS
 
57. Fujii Y, Kaneko MK, Ogasawara S, Yamada S, Yanaka M, Nakamura T, Saidoh N, Yoshida K, Honma R, Kato Y.
(*corresponding author)

Development of RAP Tag, a Novel Tagging System for Protein Detection and Purification
Open Access
Monoclon. Antib. Immunodiagn. Immunother., 36(2): 68-71, 2017 (PDF)
 
PDIS
 
56. Kaneko MK, Yamada S, Nakamura T, Abe S, Nishioka Y, Kunita A, Fukayama M, Fujii Y, Ogasawara S, Kato Y*
(*corresponding author)

Antitumor activity of chLpMab-2, a human-mouse chimeric cancer-specific antihuman podoplanin antibody, via antibody-dependent cellular cytotoxicity

Cancer Med.,6(4): 768-777, 2017
 
PDIS
 
55. Kaneko MK*, Abe S, Ogasawara S, Fujii Y, Yamada S, Murata T, Uchida H, Tahara H, Nishioka Y, Kato Y*.
(*corresponding author)

Chimeric Anti-human Podoplanin Antibody NZ-12 of Lambda Light Chain Exerts Higher Antibody-dependent Cellular Cytotoxicity and Complement-dependent Cytotoxicity Compared with NZ-8 of Kappa Light Chain

Monoclon. Antib. Immunodiagn. Immunother., 36(1): 25-29, 2017 PDIS
 
54. Kato Y*, Kunita A, Fukayama M, Abe S, Nishioka Y, Uchida H, Tahara H, Yamada S, Yanaka M, Nakamura T, Saidoh N, Yoshida K, Fujii Y, Honma R, Takagi M, Ogasawara S, Murata T, Kaneko MK*
(*corresponding author)

Anti-Glycopeptide Mouse Monoclonal Antibody LpMab-21 Exerts Antitumor Activity Against Human Podoplanin via Antibody-Dependent Cellular Cytotoxicity and Complement-Dependent Cytotoxicity

Monoclon. Antib. Immunodiagn. Immunother., 36(1): 20-24, 2017
 
PDIS
 
53．Ogasawara S, Honma R, Kaneko MK, Fujii Y, Kagawa Y, Konnai S, Kato Y*
(*corresponding author)

Podoplanin Expression in Canine Melanoma

Monoclon. Antib. Immunodiagn. Immunother., 35(6): 304-306, 2016
 
PDIS
 
52. Kaneko MK, Nakamura T, Honma R, Ogasawara S, Fujii Y, Abe S, Takagi M, Harada H, Suzuki H, Nishioka Y, Kato Y*.

Development and characterization of anti-glycopeptide monoclonal antibodies against human podoplanin using glycan-deficient cell lines generated by CRISPR/Cas and TALEN

Cancer Med.,6(2); 382?396, 2017
 
PDIS
 
51. Yuki Fujii, Mika K. Kaneko, Yukinari Kato.
 
MAP tag: A novel tagging system for protein purification and detection.
 
Monoclon. Antib. Immunodiagn. Immunother., 35(6): 293-299, 2016
 
PDIS
 
50．Mika K. Satoshi Ogasawara, Yuki Fujii, Mika K. Kaneko, Hiroharu Oki, Hemragul Sabit, Mitsutoshi Nakada, Hiroyoshi Suzuki, Koichi Ichimura, Takashi Komori, Yukinari Kato*.
(*corresponding author)

Establishment of Anti-Human ATRX Monoclonal Antibody AMab-6.

Monoclon. Antib. Immunodiagn. Immunother., 35(5): 254-258, 2016
PDIS
 
 
49．Mika K. Kaneko, Ryusuke Honma, Satoshi Ogasawara, Yuki Fujii, Takuro Nakamura, Noriko Saidoh, Michiaki Takagi, Yumiko Kagawa, Satoru Konnai, Yukinari Kato*.
(*corresponding author)

PMab-38 recognizes canine podoplanin of squamous cell carcinomas.

Monoclon. Antib. Immunodiagn. Immunother.,35(5): 263-266, 2016
PDIS
 
48. Umitsu M, Sakai K, Ogasawara S, Kaneko MK, Asaki R, Tamura-Kawakami K, Kato Y, Matsumoto K, Takagi J.

Probing conformational and functional states of human hepatocyte growth factor by a panel of monoclonal antibodies

Scientific Reports, 6, Article number: 33149

PDIS
 
47. Kitago Y, Kaneko MK, Ogasawara S, Kato Y*, Takagia J*

Structural basis for multi-specific peptide recognition by the anti-IDH1/2 monoclonal antibody, MsMab-1

Biochemical and Biophysical Research Communications, 478(3):1274-9., 2016

PDIS
 
46．Yamamichi A, Kasama T, Ohka F, Suzuki H, Kato A, Motomura K, Hirano M, Ranjit M, Chalise L, Kurimoto K, Kondo G, Aoki K, Kaji N, Tokeshi M, Matsubara T, Senga T, Kaneko MK, Suzuki H, Wakabayashi T, Baba Y, Kato Y, Natsume A.

An immuno-wall microdevice exhibits rapid and sensitive detection of IDH1-R132H mutation specific to grade II and III gliomas

Sci Technol Adv Mater., 17; 618-625, 2016
PDIS
 
45. Hayashi A, Misumi K, Shibahara J, Kokudo N, Kato Y and Fukayama M.

Immunohistochemistry Using Monoclonal Antibody MsMab-2 Is Useful to Detect IDH1 R132L in Intrahepatic Cholangiocarcinoma.

Pathology international, 66(10); 578-582, 2016
PDIS
 
 
44. Ogasawara S, Kaneko MK, Kato Y*
(*corresponding author)

LpMab-19 Recognizes Sialylated O-glycan on Thr76 of Human Podoplanin

Monoclon. Antib. Immunodiagn. Immunother., 35(5): 245-253, 2016

PDIS
 
43．Abe S, Kaneko MK, Tsuchihashi Y, Izumi T, Okada N, Miyamoto R, Sato C, Tobiume M, Otsuka K, Tsuchiya K, Kawazoe K, Ogasawara S, Kato Y, and Nishioka Y.

Antitumor effect of novel anti-podoplanin antibody NZ-12 against malignant pleural mesothelioma in orthotopic xenograft model

Cancer Sci.107, 1198-1205, 2016
PDIS
 
42．Ryusuke Honma, Mika K. Kaneko, Satoshi Ogasawara, Yuki Fujii, Satoru Konnai, Michiaki Takagi, Yukinari Kato * (*corresponding author)

Specific Detection of Dog Podoplanin Expressed in Renal Glomerulus by A Novel Monoclonal Antibody PMab-38 in Immunohistochemistry.

Monoclon. Antib. Immunodiagn. Immunother., 35(4): 212-216, 2016

PDIS
 
41．Maekawa N, Konnai S, Okagawa T, Nishimori A, Ikebuchi R, Izumi Y, Takagi S, Kagawa Y, Nakajima C, Suzuki Y, Kato Y, Murata S, Ohashi K.

Immunohistochemical Analysis of PD-L1 Expression in Canine Malignant Cancers

PLoS ONE, e0157176, 2016

PDIS
 
40．Honma R, Ogasawara S, Kaneko MK, Fujii Y, Oki H, Nakamura T, Takagi M, Konnai S, Kato Y * (*corresponding author)

PMab-44 Detects Bovine Podoplanin in Immunohistochemistry

Monoclon. Antib. Immunodiagn. Immunother., 35(4): 186-190, 2016

PDIS
 
39. Kato Y*, Ogasawara S, Oki H, Goichberg P, Honma R, Fujii Y, Kaneko MK.
(*corresponding author)
 
LpMab-12 Established by CasMab Technology Specifically Detects Sialylated O-glycan on Thr52 of Platelet Aggregation-stimulating Domain of Human Podoplanin
 
PLoS ONE, 11(3): e0152912., 2016
PDIS
 
38.山形大学整形外科、高木教授のラボからの論文
Takakubo Y, Oki H, Naganuma Y, Saski K, Sasaki A, Tamaki Y, Suran Y, Konta T, Takagi M.
 
Distribution of podoplanin in synovial tissues in rheumatoid arthritis patients using biologic or conventional disease-modifying anti-rheumatic drugs.
 
Curr Rheumatol Rev. 2016 Mar 31. [Epub ahead of print]
PDIS
 
37.山形大学医学部解剖学、後藤教授のラボからの論文
Hozumi Y, Tanaka T, Nakano T, Matsui H, Nasu T, Koike S, Kakehata S, Ito T, Goto K.
 
Orotate phosphoribosyltransferase localizes to the Golgi complex and its expression levels affect the sensitivity to anti-cancer drug 5-fluorouracil.
 
Biomedical Research 2015; 36(6): 403-409.
PDIS
 
36.山形大学医学部解剖学、後藤教授のラボからの論文
Hozumi Y, Nakano T, Tanaka T, Goto K.
 
Localization of diacylglycerol kinase ζ in rat pancreatic islet cells under normal and streptozotocin-induced stress conditions.
 
Archives of Histology and Cytology 2016; 76: 23-33.
PDIS
 
35. Ogasawara S, Kaneko MK, Honma R, Oki H, Fujii Y, Takagi M, Suzuki H, Kato Y* (*corresponding author)

Establishment of Mouse Monoclonal Antibody LpMab-13 against Human Podoplanin

Monoclon. Antib. Immunodiagn. Immunother.,DOI: 10.1089/mab.2016.0006.rev, 2016
PDIS
 
34．Fujii Y, Matsunaga Y, Arimoria T, Kitagoa Y, Ogasawara O, Kaneko MK, Kato Y, Takagi J.
 
Tailored placement of a turn-forming PA tag into the structured domain of a protein to probe its conformational state
 
J Cell Sci,,29(7):1512-22, 2016
PDIS
 
33．Honma R, Fujii Y, Ogasawara S, Oki H, Konnai S, Kagawa Y, Takagi M, Kaneko MK, Kato Y * (*corresponding author)

Critical Epitope of Anti-Rabbit Podoplanin Monoclonal Antibodies for Immunohistochemical Analysis

Monoclon. Antib. Immunodiagn. Immunother., 35(2): 65-72, 2016
PDIS
 
32． Kato Y*, Ogasawara Y, Oki H, Honma R, Takagi M, Fujii Y, Nakamura T, Saidoh N, Kanno H, Umetsu M, Kamata S, Kubo H, Yamada M, Sawa Y, Morita K, Harada H, Suzuki H, Kaneko MK. (*corresponding author)

Novel Monoclonal Antibody LpMab-17 Developed by CasMab Technology Distinguishes Human Podoplanin from Monkey Podoplanin

Monoclon. Antib. Immunodiagn. Immunother., 35(2): 109-116, 2016
PDIS
 
31．Shiina S, Ohno M, Ohka F, Kuramitsu S, Yamamichi A, Kato A, Motomura K, Tanahashi K, Yamamoto T, Watanabe R, Ito I, Senga T, Hamaguchi M, Wakabayashi T, Kaneko MK, Kato Y, Chandramohan V, Bigner DD, Natsume A.

CAR T cells targeting podoplanin reduce orthotopic glioblastomas in mouse brains

Cancer Immunology Research,, 4(3):259-68.,2016

PDIS
 
30．Honma R, Fujii Y, Ogasawara S, Oki H, Liu X, Nakamura T, Kaneko MK, Takagi M, Kato Y* (*corresponding author)

Establishment of a novel monoclonal antibody PMab-32 against rabbit podoplanin

Monoclon. Antib. Immunodiagn. Immunother., 35(1): 41-47, 2016
PDIS
 
29．Fujii Y, Ogasawara S, Oki H, Liu X, Kaneko MK, Takano S, Kato Y* (*corresponding author)

A high-sensitive HMab-2 specifically detects IDH1-R132H, the most common IDH mutation in gliomas

Biochem Biophys Res Commun., 466(4),733-739, 2015
PDIS
 
28．Oki H, Honma R, Ogasawara S, Fujii Y, Liu X, Kaneko MK, Takagi M, Kato Y* (*corresponding author)

Development of a sensitive monoclonal antibody PMab-2 against rat podoplanin

Monoclon. Antib. Immunodiagn. Immunother., 34(6): 396-403, 2015
PDIS
 
27．Kato Y*, Kunita A, Abe S, Ogasawara S, Fujii Y, Oki H, Fukayama M, Nishioka Y, and Kaneko MK. (*corresponding author)

The chimeric antibody chLpMab-7 targeting human podoplanin suppresses pulmonary metastasis via ADCC and CDC rather than via its neutralizing activity.

Oncotarget,6(34): 36003-36018, 2015
PDIS
 
26．Ogasawara S, Oki H, Kaneko MK, Hozumi Y, Liu X, Honma R, Fujii Y, Nakamura T, Goto K, Takagi M, Kato Y* (*corresponding author)

Development of a monoclonal antibody LpMab-10 recognizing non-glycosylated PLAG1/2 domain including Thr34 of human podoplanin.

Monoclon. Antib. Immunodiagn. Immunother., 34(5): 318-326, 2015
PDIS
 
25．Ikota H, Nobusawa S, Arai H, Kato Y, Ishizawa K, Hirose T, Yokoo H.

Evaluation of IDH1 status in diffusely infiltrating gliomas by immunohistochemistry using anti-mutant and wild type IDH1 antibodies

Brain Tumor Pathol., 32(4):237-44, 2015
PDIS
 
24． Kaneko MK, Oki H, Hozumi Y, Liu X, Ogasawara S, Takagi M, Goto K, Kato Y* (*corresponding author)

A monoclonal antibody LpMab-9 recognizes O-glycosylated N-terminus of human podoplanin.

Monoclon. Antib. Immunodiagn. Immunother.,34(5): 310-317, 2015
PDIS
 
23．Liu X, Ogasawara S, Kaneko MK, Oki H, Hozumi Y, Goto K, Takagi M, Kato Y.* (*corresponding author)

A novel monoclonal antibody SMab-2 recognizes endogenous IDH2-R172S of chondrosarcoma

Biochem Biophys Res Commun., 459(4),636?642, 2015
PDIS
 
22．Oki H, Kaneko MK, Ogasawara S, Tsujimoto Y, Liu X, Sugawara M, Takakubo Y, Takagi M, Kato Y* (*corresponding author)

Characterization of a monoclonal antibody LpMab-7 recognizing non-PLAG domain of podoplanin

Monoclon. Antib. Immunodiagn. Immunother., 34(3): 174-180, 2015
PDIS
 
21．Kaneko MK, Oki H, Ogasawara S, Takagi M, Kato Y* (*corresponding author)

An anti-podoplanin monoclonal antibody LpMab-7 detects metastatic legions of osteosarcoma

Monoclon. Antib. Immunodiagn. Immunother.,34(3): 154-161, 2015
PDIS
 
20．Jhon A. Ochoa-Alvarez, Harini Krishnan, John G. Pastorino, Evan Nevel, David Kephart, Yongquan Shen, Mahnaz Fatahzadeh, Soly Baredes, Evelyne Kalyoussef, Masaru Honma, Martin E. Adelson, Mika K. Kaneko, Yukinari Kato, Kingsley Yin, Alan J. Shienbaum, Lasse D. Jensen, and Gary S. Goldberg

Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms.

Oncotarget,6(11),9045-9060,2015
PDIS
 
19．Takano S, Kato Y, Yamamoto T, Liu X, Ishikawa E, Kaneko MK, Ogasawara S, Matsuda M, Noguchi M, Matsumura A.

Diagnostic advantage of double immunohistochemistry using two mutation-specific anti-IDH antibodies (HMab-1 and MsMab-1) in gliomas.

Brain Tumor Pathol., DOI: 10.1007/s10014-015-0214-8; Volume 32, Issue 3, pp 169-175, 2015
PDIS
 
18. Oki H, Ogasawara S, Kaneko MK, Takagi M, Yamauchi Y, Kato Y.*(*corresponding author)

Characterization of a monoclonal antibody LpMab-3 recognizing sialylated glycopeptide of podoplanin.

Monoclon. Antib. Immunodiagn. Immunother., 34(1): 44-50, 2015
PDIS
 
17.Yukinari Kato
 
Specific monoclonal antibodies against IDH1/2 mutations as diagnostic tools for gliomas. Brain tumor pathology, Volume 32, Issue 1, pp 3-11, 2015
PDIS
 
16. Nagae M, Morita-Matsumoto K, Kato M, Kaneko MK, Kato Y, Yamaguchi Y.
 
A novel platform of C-type lectin-like receptor CLEC-2 for binding O-glycosylated podoplanin and non-glycosylated rhodocytin.
 
Structure, Volume 22, Issue 12, 1711-1721（理研との共同研究@東北大学）
PDIS
 
15. 山形大学医学部解剖学、後藤教授のラボからの論文
Matsui H, Hozumi Y, Tanaka T, Okada M, Nakano T, Suzuki Y, Iseki K, Kakehata S, Topham MK, Goto K.
 
Role of the N-terminal hydrophobic residues of DGKε in targeting the endoplasmic reticulum. Biochim Biophys Acta. 2014 Oct;1842(10):1440-50. PDIS
 
14. Kato Y* and Kaneko MK.(*corresponding author)
 
A Cancer-specific Monoclonal Antibody Recognizes the Aberrantly Glycosylated Podoplanin.
 
Sci Rep 4, 5924, 2014（@東北大学）（注目の論文）
PDIS
 
13. Maruyama Y, Maruyama K, Kato Y, Kajiya K, Moritoh S, Yamamoto K, Matsumoto Y, Kerjaschki D, Nakazawa T, Kinoshita S.
 
The Effect of Podoplanin Inhibition on Lymphangiogenesis under Pathological Conditions.
 
Invest Ophthalmol Vis Sci., 55:4813-4822; 2014（眼科との共同研究@東北大学）PDIS
 
12. Kaneko M, Liu X, Oki H, Ogasawara S, Nakamura T, Saidoh N, Tsujimoto Y, Matsuyama Y, Uruno A, Sugawara M, Tsuchiya T, Yamakawa M, Yamamoto M, Takagi M, Kato Y.* (*corresponding author)
 
IDH2 mutation is frequently observed in giant cell tumor of bone.
 
Cancer Sci.,105(6),744-748,2014 （医化学、山形大学整形外科との共同研究@東北大学）PDIS
 
11. Ohka F, Ito M, Ranjit M, Senga T, Motomura A, Motomura K, Saito K, Kato K, Kato Y, Wakabayashi T, Soga T, Natsume A.
 
Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutaion
 
Tumor Biol., 35(6):5911-20（名古屋大学、慶応大学先端研との共同研究@東北大学） PDIS
 
10. Fujii Y, Kaneko M, Neyazaki M, Nogi T, Kato Y*, Takagi J*(*corresponding author)
 
PA tag: a versatile protein tagging system using a super high affinity antibody against a dodecapeptide derived from human podoplanin.
 
Protein Expr Purif. Volume 95, 240-247, 2014（pdf）（大阪大学との共同研究@東北大学）PDIS
 
9. Moriya K*, Kaneko MK, Liu X, Hosaka M, Fujishima F, Watanabe M, Ogasawara S, Sakuma J, Sasahara Y, Kure S, Kato Y*(*corresponding author)
 
IDH2 and TP53 mutations are correlated with gliomagenesis in a patient with Maffucci syndrome.
 
Cancer Sci., 105(3),359-362,2014（小児科、整形外科との共同研究@東北大学）PDIS
 
8. Liu X, Kato Y*, Kaneko MK, Sugawara M, Ogasawara S, Tsujimoto Y, Naganuma Y, Yamakawa M, Tsuchiya T, Takagi M.(*corresponding author)
 
Isocitrate dehydrogenase 2 mutation is a frequent event in osteosarcoma detected by a multi-specific monoclonal antibody MsMab-1.
 
Cancer Med.,2(6): 803-814, 2013（PDF）（山形大学整形外科との共同研究@東北大学）PDIS
 
7. Ogasawara S, Kaneko MK, Tsujimoto Y, Liu X, Kato Y*.(*corresponding author)
 
A Multi-specific Monoclonal Antibody MsMab-2 Recognizes IDH1-R132L and IDH2-R172M Mutations.
 
Monoclon. Antib. Immunodiagn. Immunother., 32(6), 377-381, 2013（pdf）（@東北大学）PDIS
 
6. Kaneko MK, Ogasawara S, Kato Y*. (*corresponding author)
 
Establishment of a novel multi-specific monoclonal antibody MsMab-1 recognizing both IDH1 and IDH2 mutations.
 
TJEM, 230: 103-109, 2013（@東北大学）PDIS
 
5. Abe S, Morita Y, Kaneko MK, Hanibuchi M, Tsujimoto Y, Goto H, Kakiuchi S, Aono Y, Huang J, Sato S, Kishuku M, Taniguchi Y, Azuma M, Kawazoe K, Sekido Y, Yano S, Akiyama S, Sone S, Minakuchi K, Kato Y, Nishioka Y
 
A novel targeting therapy of malignant mesothelioma using anti-podoplanin antibody.
 
J. Immunol., 190(12):6239-49（pdf）（徳島大学との共同研究@山形大学）PDIS
 
4. Kaneko MK, Tsujimoto Y, Hozumi Y, Goto K, Kato Y*.(*corresponding author)
 
Novel monoclonal antibodies GMab-r1 and LMab-1 specifically recognize IDH1-R132G and IDH1-R132L mutations
 
Monoclon. Antib. Immunodiagn. Immunother., 32(3), 224-228, 2013（PDF）（山形大学解剖学との共同研究@山形大学）PDIS
 
3. Kato Y* and Kaneko MK. (*corresponding author)
 
Generation of a novel monoclonal antibody WMab-1 specific for IDH2-R172W mutation
 
Biochem Biophys Res Commun., 433(4), 374–378, 2013 （pdf）（@山形大学）PDIS
 
2. Kato Y*, Natsume A, Kaneko MK, (*corresponding author)
 
A novel monoclonal antibody GMab-m1 specifically recognizes IDH1-R132G mutation
 
Biochem Biophys Res Commun., 432(4):564-7, 2013 （pdf） （名古屋大学との共同研究@山形大学）PDIS
 
1. Kaneko MK, Morita S, Tsujimoto Y, Yanagiya R, Nasu K, Sasaki H, Hozumi Y, Goto K, Natsume A, Watanabe M, Kumabe T, Takano S, Kato Y*(*corresponding author)
 
Establishment of novel monoclonal antibodies KMab-1 and MMab-1 specific for IDH2 mutations
 
Biochem Biophys Res Commun., 432(1):40-5, 2013（東北大学、名古屋大学との共同研究@山形大学）PDIS
 
・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・
 

＊大型プロジェクト：2012年8月から創薬PF開始。同年10月から地域イノベ開始（加藤が教授に着任）。2013年4月から東北大学に異動。2014年10月から革新的バイオ開始。2016年9月から糖鎖創薬開始。同年9月から橋渡し（研究シーズB）開始。2017年４月から、創薬LS (BINDS)開始。同４月から、共同研究講座開始。


＊PubMed（加藤の2003年以降の業績）
＊Google scholar（加藤）
＊PDISの謝辞入り文献
＊革新的バイオの謝辞入り文献
＊糖鎖創薬の謝辞入り文献
＊東大医科研共同研究員の謝辞入り文献
＊阪大蛋白研共同研究員の謝辞入り文献

＊創薬プラットフォーム事業の成果（謝辞に記載）にはPDISと記載しています。

＊参考：インパクトファクター





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