次世代治療･診断実現のための創薬基盤技術開発事業
(糖鎖利用による革新的創薬技術開発事業)
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＊論文に糖鎖創薬の謝辞（This research was supported by AMED under Grant Number JP18ae0101028. ）を入れた論文を紹介します。
論文一覧
＊in press ~ online掲載論文については、抗体創薬研究分野の業績参照。
2021
110. Sayama Y, Kaneko MK, Takei J, Hosono H, Sano M, Asano T, Kato Y.
Establishment of a novel anti-TROP2 monoclonal antibody TrMab-29 for immunohistochemical analysis
Biochem Biophys Rep.,25, 100902, https://doi.org/10.1016/j.bbrep.2020.100902, 2021 (PDF)
109. Yusuke Sayama, Mika K. Kaneko, Yukinari Kato.
Development and characterization of TrMab-6, a novel anti-TROP2 monoclonal antibody for antigen detection in breast cancer
Molecular Medicine Reports, 23(2), article number-92, https://doi.org/10.3892/mmr.2020.11731, 2021 (PDF)
2020
108. Kamoto S, Shinada M, Kato D, Yoshimoto S, Ikeda N, Tsuboi M, Yoshitake R, Eto S, Hashimoto Y, Takahashi Y, Chambers J, Uchida K, Kaneko MK, Fujita N, Nishimura R, Kato Y, Nakagawa T.
Phase I/II Clinical Trial of the Anti-Podoplanin Monoclonal Antibody Therapy in Dogs with Malignant Melanoma
Cells, 9(11), 2529; https://doi.org/10.3390/cells9112529, 2020 (PDF)
107. Kaneko MK, Ohishi T, Takei J, Sano M, Nakamura T, Hosono H, Yanaka M, Asano T, Sayama Y, Harada H, Kawada M, Kato Y.*
(*corresponding author)
The Anti-EpCAM monoclonal antibody (EpMab-16) exerts anti-tumor activity against oral squamous cell carcinomas
Oncol Rep., 44(6), 2517-2526, https://doi.org/10.3892/or.2020.7808, 2020 (PDF)
106. Hosono H, Ohishi T, Takei J, Asano T, Sayama Y, Kawada M, Kaneko MK, Kato Y.*
(*corresponding author)
The anti-EpCAM monoclonal antibody EpMab-16 exerts antitumor activity in a mouse model of colorectal adenocarcinoma
Oncol Lett., 20: 383, https://www.spandidos-publications.com/10.3892/ol.2020.12246, 2020 (PDF)
105. Kaneko MK, Ohishi T, Nakamura T, Inoue H, Takei J, Sano M, Asano T, Sayama Y, Hosono H, Suzuki H, Kawada M, Kato Y.*
(*corresponding author)
Development of Core-fucose Deficient Humanized and Chimeric Anti-Human Podoplanin Antibodies
Monoclon. Antib. Immunodiagn. Immunother., 39(5), 167–174, https://doi.org/10.1089/mab.2020.0019, 2020 (PDF)
104. Ogasawara S, Suzuki K, Naruchi K, Nakamura S, Shimabukuro J, Tsukahara N, Kaneko MK, Kato Y, Murata T.
Crystal structure of an anti-podoplanin antibody bound to a disialylated O-linked glycopeptide
Biochem Biophys Res Commun., 533(1), 57-63, https://doi.org/10.1016/j.bbrc.2020.08.103, 2020 (PDF)
103. Kaneko MK, Ohishi T, Kawada M, Kato Y.
A cancer-specific anti-podocalyxin monoclonal antibody (60-mG2a-f) exerts antitumor effects in mouse xenograft models of pancreatic carcinoma
Biochem Biophys Rep., 24, 100826, https://doi.org/10.1016/j.bbrep.2020.100826, 2020 (PDF)
102. Takei J, Kaneko MK, Ohishi T, Hosono H, Nakamura T, Yanaka M, Sano M, Asano T, Sayama Y, Kawada M, Harada H, Kato Y.*
(*corresponding author)
A defucosylated anti-CD44 monoclonal antibody 5-mG2a-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
Oncol Rep., 44: 1949-1960, https://doi.org/10.3892/or.2020.7735, 2020 (PDF)
101. Miura K, Yoshida H, Nosaki S, Kaneko MK, Kato Y.
RAP tag and PMab-2 antibody: a tagging system for detecting and purifying proteins in plant cells
Front. Plant Sci.,11, 510444, doi: 10.3389/fpls.2020.510444, 2020 (PDF)
100. Sano M, Asano T, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope mapping of an anti-diacylglycerol kinase delta monoclonal antibody DdMab-1
Biochem Biophys Rep., 24, 100808, https://doi.org/10.1016/j.bbrep.2020.100808, 2020 (PDF)
99. Takei J, Ohishi T, Kaneko MK, Harada H, Kawada M, Kato Y.*
(*corresponding author)
A defucosylated anti-PD-L1 monoclonal antibody 13-mG2a-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
Biochem Biophys Rep.,, 24, 100801, https://doi.org/10.1016/j.bbrep.2020.100801, 2020 (PDF)
98. Kaneko MK, Sano M, Takei J, Asano T, Sayama Y, Hosono H, Kobayashi A, Konnai S, Kato Y.*
(*corresponding author)
Development and Characterization of Anti-Sheep Podoplanin Monoclonal Antibodies PMab-253 and PMab-260
Monoclon. Antib. Immunodiagn. Immunother., 39(4):144–155 DOI: 10.1089/mab.2020.0018, 2020 (PDF)
97. Furusawa Y, Kaneko MK, Kato Y*
(*corresponding author)
Establishment of an Anti-CD20 Monoclonal Antibody (C20Mab-60) for Immunohistochemical Analyses
Monoclon. Antib. Immunodiagn. Immunother.,39(4):112–116, DOI: 10.1089/mab.2020.0015, 2020 (PDF)
96. Kato Y*, Ohishi T, Takei J, Nakamura T, Kawada M, Kaneko MK.
(*corresponding author)
An anti-human epidermal growth factor receptor 2 monoclonal antibody (H2Mab-19) exerts antitumor activity in glioblastoma xenograft models
Monoclon. Antib. Immunodiagn. Immunother.,39(4):135–139, https://doi.org/10.1089/mab.2020.0013, 2020 (PDF)
95.Sano M, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope mapping of DhMab-1, an anti-diacylglycerol kinase monoclonal antibody
Monoclon. Antib. Immunodiagn. Immunother.,39(4):140–143, https://doi.org/10.1089/mab.2020.0014, 2020 (PDF)
94. Kato Y*, Ohishi T, Takei J, Nakamura T, Sano M, Asano T, Sayama Y, Hosono H, Kawada M, Kaneko MK.
(*corresponding author)
An anti-human epidermal growth factor receptor 2 monoclonal antibody H2Mab-19 exerts antitumor activity in mouse colon cancer xenografts
Monoclon. Antib. Immunodiagn. Immunother.,39(4):123–128, doi:10.1089/mab.2020.0009, 2020 (PDF)
93. Asano T, Sano M, Takei J, Sayama Y, Kaneko MK, Kato Y*
(*corresponding author)
Epitope mapping of the anti-diacylglycerol kinase monoclonal antibody DhMab-4 for immunohistochemical analysis
Monoclon. Antib. Immunodiagn. Immunother.,39(4):117–122, DOI: 10.1089/mab.2020.0012, 2020 (PDF)
92. Tomokazu Ohishi, Yukinari Kato, Mika K. Kaneko, Shun-ichi Ohba, Hiroyuki Inoue, Akiko Harakawa, Manabu Kawada.
Anti-metastatic activity of an anti-EGFR monoclonal antibody against metastatic colorectal cancer with KRAS p.G13D mutation.
Int. J. Mol. Sci., 21(17), 6037; https://doi.org/10.3390/ijms21176037, 2020 (PDF)
91. Hideki Hosono, Junko Takei, Tomokazu Ohishi, Masato Sano, Teizo Asano, Yusuke Sayama, Takuro Nakamura, Miyuki Yanaka, Manabu Kawada, Hiroyuki Harada, Mika Kato Kaneko, Yukinari Kato*
(*corresponding author)
The anti-EGFR monoclonal antibody 134-mG2a exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
International Journal of Molecular Medicine, 46(4), 1443-1452, 2020, https://doi.org/10.3892/ijmm.2020.4700 (PDF)
90. Asano T, Kaneko MK, Kato Y.*
(*corresponding author)
RIEDL tag: A novel pentapeptide tagging system for transmembrane protein purification
Biochem Biophys Rep., 23, 100780; https://doi.org/10.1016/j.bbrep.2020.100780, 2020 (PDF)
89. Kato Y*, Sano M, Asano T, Sayama Y, Kaneko MK.
(*corresponding author)
Thr80 of sheep podoplanin is a critical epitope of the anti-sheep podoplanin monoclonal antibody, PMab-256
Monoclon. Antib. Immunodiagn. Immunother., 39(3):95–100, https://doi.org/10.1089/mab.2020.0010, 2020 (PDF)
88. Kato Y*, Ohishi T, Sano M, Asano T, Sayama Y, Takei J, Kawada M, Kaneko MK.
(*corresponding author)
H2Mab-19 anti-human epidermal growth factor receptor 2 monoclonal antibody therapy exerts antitumor activity in pancreatic cancer xenograft models
Monoclon. Antib. Immunodiagn. Immunother., 39(3):61–65; , https://doi.org/10.1089/mab.2020.0011, 2020 (PDF)
87. Kato Y*, Takei J, Sano M, Asano T, Sayama Y, Uchida K, Nakagawa T, Kaneko MK.
(*corresponding author)
Detection of lion podoplanin using the anti-tiger podoplanin monoclonal antibody PMab-231
Monoclon. Antib. Immunodiagn. Immunother., 39(3):91–94; , https://doi.org/10.1089/mab.2020.0008, 2020 (PDF)
86. Kato Y*, Furusawa Y, Sano M, Takei J, Nakamura T, Yanaka M, Okamoto S, Handa S, Komatsu Y, Asano T, Sayama Y, Kaneko MK.
(*corresponding author)
Development of an Anti-Sheep Podoplanin Monoclonal Antibody PMab-256 for Immunohistochemical Analysis of Lymphatic Endothelial Cells
Monoclon. Antib. Immunodiagn. Immunother., 39(3):82–90; DOI: 10.1089/mab.2020.0005, 2020 (PDF)
85. Sayama Y, Sano M, Asano T, Furusawa Y, Takei J, Nakamura T, Yanaka M, Okamoto S, Handa S, Komatsu Y, Nakamura Y, Yanagawa M, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope mapping of PMab-241, a lymphatic endothelial cell-specific anti-bear podoplanin monoclonal antibody
Monoclon. Antib. Immunodiagn. Immunother., 39(3):77–81; DOI: 10.1089/mab.2020.0004, 2020 (PDF)
84. Mukai C, Choi E, Sams KL, Klampen EZ, Anguish L, Marks BA, Rice EJ, Wang Z, Choate LA, Chou SP, Kato Y, Miller AD, Danko CG, Coonrod SA.
Chromatin run-on sequencing analysis finds that ECM remodeling plays an important role in canine hemangiosarcoma pathogenesis
BMC Veterinary Research, 16:206, DOI: 10.1186/s12917-020-02395-3, 2020 (PDF)
83. Furusawa Y, Kaneko MK, Kato Y.*
(*corresponding author)
Establishment of C20Mab-11, a novel anti-CD20 monoclonal antibody, for the detection of B cells
Oncol Lett., 20(2), 1961-1967; https://doi.org/10.3892/ol.2020.11753, 2020 (PDF)
82. Junko Takei, Mika K. Kaneko, Tomokazu Ohishi, Manabu Kawada, Hiroyuki Harada, Yukinari Kato*
(*corresponding author)
H2Mab-19, an anti-human epidermal growth factor receptor 2 monoclonal antibody exerts antitumor activity in mouse oral cancer xenografts
Exp Ther Med., 20: 846-853, https://doi.org/10.3892/etm.2020.8765, 2020 (PDF)
81. Shinada M, Kato D, Kamoto S, Yoshimoto S, Tsuboi M, Yoshitake R, Eto S, Ikeda N, Saeki K, Hashimoto Y, Takahashi Y, Chambers J, Uchida K, Kaneko MK, Fujita N, Nishimura R, Kato Y, Nakagawa T.
PDPN is expressed in various types of canine tumors and its silencing induces apoptosis and cell cycle arrest in canine malignant melanoma
Cells, 9(5):E1136. doi: 10.3390/cells9051136., 2020 (PDF)
80. Nishinaga Y, Sato K, Yasui H, Taki S, Takahashi K, Shimizu M, Endo R, Koike C, Kuramoto N, Nakamura S, Fukui T, Yukawa H, Baba Y, K Kaneko M, Chen-Yoshikawa TF, Kobayashi H, Kato Y, Hasegawa Y.
Targeted Phototherapy for Malignant Pleural Mesothelioma: Near-Infrared Photoimmunotherapy Targeting Podoplanin
Cells,9(4), 1019; https://doi.org/10.3390/cells9041019, 2020 (PDF)
79. Kato Y*, Ito Y, Ohishi T, Kawada M, Nakamura T, Sayama Y, Sano M, Asano T, Yanaka M, Okamoto S, Handa S, Komatsu Y, Takei J, Kaneko MK.
(*corresponding author)
Antibody–drug conjugates using mouse–canine chimeric anti-dog podoplanin antibody exerts antitumor activity in a mouse xenograft model
Monoclon. Antib. Immunodiagn. Immunother., 39(2); 37-44; https://doi.org/10.1089/mab.2020.0001, 2020 (PDF)
78. Yamada S, Kaneko MK, Sayama Y, Asano T, Sano M, Yanaka M, Nakamura T, Okamoto S, Handa S, Komatsu Y, Nakamura Y, Furusawa Y, Takei J, Kato Y.*
(*corresponding author)
Development of novel mouse monoclonal antibodies against human CD19
Monoclon. Antib. Immunodiagn. Immunother., 39(2);45-50; DOI: 10.1089/mab.2020.0003, 2020 (PDF)
77. Kuwata T, Yoneda K, Mori M, Kanayama M, Kuroda K, Kaneko MK, Kato Y, Tanaka F.
Effective detection of circulating tumor cells (CTCs) in malignant pleural mesothelioma (MPM) with the "universal" CTC-chip and an anti-podoplanin antibody NZ-1.2
Cells, 9(4), 888; https://doi.org/10.3390/cells9040888, 2020 (PDF)
76. Takei J, Kaneko MK, Ohishi T, Kawada M, Harada H, Kato Y.*
(*corresponding author)
A novel anti-EGFR monoclonal antibody (EMab-17) exerts antitumor activity against oral squamous cell carcinomas via antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity
Oncol Lett., 19(4), 2809-2816, https://doi.org/10.3892/ol.2020.11384, 2020, (PDF)
75. Sayama Y, Sano M, Kaneko MK, Kato Y*
(*corresponding author)
Epitope analysis of an anti-whale podoplanin monoclonal antibody, PMab-237, using flow cytometry
Monoclon. Antib. Immunodiagn. Immunother., 39(1):17-22, https://doi.org/10.1089/mab.2019.0045, 2020, (PDF)
74.Sano M, Kaneko MK, Suzuki H, Kato Y.*
(*corresponding author)
Establishment and Epitope Mapping of Anti-Diacylglycerol Kinase Alpha Monoclonal Antibody DaMab-8 for immunohistochemical analyses
Monoclon. Antib. Immunodiagn. Immunother., 39(1):1-5, doi: 10.1089/mab.2019.0004.(PDF)
2019
73. Sayama Y, Sano M, Furusawa Y, Kaneko MK, Kato Y*
(*corresponding author)
Epitope Mapping of PMab-225 an Anti-Alpaca Podoplanin Monoclonal Antibody using Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother., 38(6):255–260, DOI: 10.1089/mab.2019.0033, 2019 (PDF)
72. Takei J, Yamada S, Konnai S, Ishinazaka T, Shimozuru M, Kaneko MK, Kato Y.*
(*corresponding author)
PMab-241 Specifically Detects Bear Podoplanin of Lymphatic endothelial cells in the Lung of Brown Bear
Monoclon. Antib. Immunodiagn. Immunother., 38(6):282–284, https://doi.org/10.1089/mab.2019.0038, 2019 (PDF)
71. Kaneko MK, Sayama Y, Sano M, Kato Y.*
(*corresponding author)
The Epitope of PMab-210 is Located in Platelet Aggregation-Stimulating Domain-3 of Pig Podoplanin
Monoclon. Antib. Immunodiagn. Immunother.,38(6):271–276, https://doi.org/10.1089/mab.2019.0037, 2019 (PDF)
70. Kato Y*, Sayama Y, Sano M, Kaneko MK.
(*corresponding author)
Epitope Analysis of an Anti-Horse Podoplanin Monoclonal Antibody PMab-219
Monoclon. Antib. Immunodiagn. Immunother.,38(6):266–270 https://doi.org/10.1089/mab.2019.0034, 2019 (PDF)
69. Sano M, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope Mapping of Monoclonal Antibody PMab-233 Against Tasmanian Devil Podoplanin
Monoclon. Antib. Immunodiagn. Immunother.,38(6): 261–265, DOI: 10.1089/mab.2019.0032, 2019 (PDF)
68. Kato Y*, Takei J, Furusawa Y, Sayama Y, Sano M, Konnai S, Kobayashi A, Harada H, Takahashi M, Suzuki H, Yamada S, Kaneko MK.
(*corresponding author)
Epitope mapping of anti-bear podoplanin monoclonal antibody PMab-247
Monoclon. Antib. Immunodiagn. Immunother., 38(5): 230–233, https://doi.org/10.1089/mab.2019.0025, 2019 (PDF)
67. Yamada S, Itai S, Furusawa Y, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope mapping of anti-pig podoplanin monoclonal antibody PMab-213
Monoclon. Antib. Immunodiagn. Immunother., 38(5): 224–229, https://doi.org/10.1089/mab.2019.0023, 2019 (PDF)
66. Takei J, Itai S, Harada H, Furusawa Y, Miwa T, Fukui M, Nakamura T, Sano M, Sayama Y, Yanaka M, Handa S, Hisamatsu K, Nakamura Y, Yamada S, Kaneko MK, Kato Y.*
(*corresponding author)
Characterization of anti-goat podoplanin monoclonal antibody PMab-235 using immunohistochemistry against goat tissues.
Monoclon. Antib. Immunodiagn. Immunother., 38(5), 213–219, https://doi.org/10.1089/mab.2019.0022, 2019 (PDF)
65. Sano M, Kaneko MK, Kato Y.*.
(*corresponding author)
Epitope Mapping of Anti-Diacylglycerol Kinase Zeta Monoclonal Antibody DzMab-1 for Immunohistochemical Analyses.
Monoclon. Antib. Immunodiagn. Immunother., 38(4), 175–178, doi: 10.1089/mab.2019.0020, 2019 (PDF)
64. Takei J, Furusawa Y, Yamada S, Nakamura T, Sayama Y, Sano M, Konnai S, Kobayashi A, Harada H, Kaneko MK, Kato Y.*.
(*corresponding author)
PMab-247 Detects Bear Podoplanin in Immunohistochemical Analysis.
Monoclon. Antib. Immunodiagn. Immunother., 38(4), 171–174, https://doi.org/10.1089/mab.2019.0019, 2019 (PDF)
63. Kato Y*, Ohishi T, Yamada S, Itai S, Takei J, Sano M, Nakamura T, Harada H, Kawada M, Kaneko MK.
(*corresponding author)
Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody H2Mab-41 Exerts Antitumor Activity in a Mouse Xenograft Model of Colon Cancer.
Monoclon. Antib. Immunodiagn. Immunother., 38(4), 157–161; https://doi.org/10.1089/mab.2019.0017, 2019 (PDF)
62. Furusawa Y, Takei J, Sayama Y, Yamada S, Kaneko MK, Kato Y.*
(*corresponding author)
Development of an anti-bear podoplanin monoclonal antibody PMab-247 for immunohistochemical analysis
Biochem Biophys Rep., Volume 18, July 2019, 100644, https://doi.org/10.1016/j.bbrep.2019.100644, 2019 (PDF)
61. Kato Y*, Furusawa Y, Yamada S, Itai S, Takei J, Sano M, Kaneko MK.
(*corresponding author)
Establishment of a monoclonal antibody PMab-225 against alpaca podoplanin for immunohistochemical analyses
Biochem Biophys Rep., Volume 18, July 2019, 100633, https://authors.elsevier.com/sd/article/S2405580818303194, 2019 (PDF)
60. Furusawa Y, Yamada S, Itai S, Nakamura T, Takei J, Sano M, Harada H, Fukui M, Kaneko MK, Kato Y. *
(*corresponding author)
Establishment of a monoclonal antibody PMab-233 for immunohistochemical analysis against Tasmanian devil podoplanin
Biochem Biophys Rep., Volume 18, July 2019, 100631, https://doi.org/10.1016/j.bbrep.2019.100631 (PDF)
59. Furusawa Y, Yamada S, Nakamura T, Sano M, Sayama Y, Itai S, Takei J, Harada H, Fukui M, Kaneko MK, Kato Y.
PMab-235: a monoclonal antibody for immunohistochemical analysis against goat podoplanin
Heliyon, 5(7), e02063, 2019 (PDF)
58. Kato Y*, Furusawa Y, Itai S, Takei J, Nakamura T, Sano M, Harada H, Yamada S, Kaneko MK.
(*corresponding author)
Establishment of an anti-cetacean podoplanin monoclonal antibody PMab-237 for immunohistochemical analysis
Monoclon. Antib. Immunodiagn. Immunother., 38(3), 108–113, https://doi.org/10.1089/mab.2019.0013, 2019 (PDF)
57. Yamada S, Itai S, Nakamura T, Takei J, Sano M, Konnai S, Kobayashi A, Nakagun S, Kobayashi Y, Kaneko MK, Kato Y.*
(*corresponding author)
Immunohistochemical analysis of the harbor porpoise using anti-podoplanin antibody PMab-237
Monoclon. Antib. Immunodiagn. Immunother., 38(3), 104–107, https://doi.org/10.1089/mab.2019.0014, 2019 (PDF)
56. Sano M, Kaneko MK, Kato Y.*.
(*corresponding author)
Epitope Mapping of Anti-Human DGKgamma Monoclonal Antibody DgMab-6
Monoclon. Antib. Immunodiagn. Immunother., 38(3), 120–123, https://doi.org/10.1089/mab.2019.0011, 2019 (PDF)
55. Kato Y*, Itai S, Yamada S, Suzuki H, Kaneko MK.
(*corresponding author)
Epitope Mapping of Anti-Diacylglycerol Kinase Zeta Monoclonal Antibody for the Detection of T cells by Immunohistochemical Analyses
Monoclon. Antib. Immunodiagn. Immunother., 38(3), 124–128, doi: 10.1089/mab.2019.0005., 2019 [Epub ahead of print](PDF)
54. Takei J, Itai S, Furusawa Y, Yamada S, Nakamura T, Sano M, Harada H, Fukui M, Kaneko MK, Kato Y*
(*corresponding author)
Epitope mapping of anti-tiger podoplanin monoclonal antibody PMab-231
Monoclon. Antib. Immunodiagn. Immunother., 38(3), 129–132, doi: 10.1089/mab.2019.0012., 2019 (PDF)
53. Kaneko MK, Yamada S, Itai S, Chang YW, Nakamura T, Yanaka M, Harada H, Suzuki H, Kato Y.*
(*corresponding author)
Elucidation of the TMab-6 Monoclonal Antibody Epitope Against Telomerase Reverse Transcriptase
Monoclon. Antib. Immunodiagn. Immunother., 38(3), 101–103, https://doi.org/10.1089/mab.2018.0007, 2019 (PDF)
52. Kato Y*, Ohishi T, Yamada S, Itai S, Furusawa Y, Sano M, Nakamura T, Kawada M, Kaneko MK.
(*corresponding author)
Anti-CD133 monoclonal antibody CMab-43 exerts antitumor activity in a mouse xenograft model of colon cancer
Monoclon. Antib. Immunodiagn. Immunother., 38(2):75–78, https://doi.org/10.1089/mab.2019.0002, 2019 (PDF)
51. Furusawa Y, Kaneko MK, Nakamura T, Itai S, Fukui M, Harada H, Yamada S, Kato Y.*
(*corresponding author)
Establishment of a monoclonal antibody PMab-231 for tiger podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 38(2):89–95, https://doi.org/10.1089/mab.2019.0003, 2019 (PDF)
50. Kaneko MK, Furusawa Y, Sano M, Itai S, Takei J, Harada H, Fukui M, Yamada S, Kato Y.*
(*corresponding author)
Epitope mapping of the anti-horse podoplanin monoclonal antibody PMab-202
Monoclon. Antib. Immunodiagn. Immunother., 38(2):79–84, https://doi.org/10.1089/mab.2019.0001, 2019 (PDF)
49. Yamada S, Kaneko MK, Furusawa Y, Itai S, Sano M, Nakamura T, Yanaka M, Handa S, Hisamatsu K, Nakamura Y, Koyanagi M, Fukui M, Harada H, Kato Y.*
(*corresponding author)
Anti-bovine podoplanin monoclonal antibody PMab-44 detects goat podoplanin in immunohistochemistry
Monoclon. Antib. Immunodiagn. Immunother., 38(2):96–99, https://doi.org/10.1089/mab.2018.0031, 2019 (PDF)
48. Furusawa Y, Yamada S, Itai S, Sano M, Nakamura T, Yanaka M, Fukui M, Harada H, Mizuno T, Sakai Y, Takasu M, Kaneko MK, Kato Y*.
(*corresponding author)
PMab-210: A Monoclonal Antibody Against Pig Podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 38(1), 30-36; https://doi.org/10.1089/mab.2018.0038, 2019 (PDF)
47. Sano M, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope Mapping of Anti-Diacylglycerol Kinase alpha Monoclonal Antibody DaMab-2
Monoclon. Antib. Immunodiagn. Immunother., 38(1), 8-11; https://doi.org/10.1089/mab.2018.0047, 2019 (PDF)
46. Kato Y*, Yamada S, Furusawa Y, Itai S, Nakamura T, Yanaka M, Sano M, Harada H, Fukui M, Kaneko MK.
(*corresponding author)
PMab-213: a monoclonal antibody for immunohistochemical analysis against pig podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 38(1), 18-24; https://doi.org/10.1089/mab.2018.0048, 2019 (PDF)
45. Furusawa Y, Yamada S, Itai S, Nakamura T, Yanaka M, Sano M, Harada H, Fukui M, Kaneko MK, Kato Y.*
(*corresponding author)
PMab-219: a monoclonal antibody for the immunohistochemical analysis of horse podoplanin
Biochem Biophys Rep., 18:100616. doi: 10.1016/j.bbrep.2019.01.009., 2019 (PDF)
44. Kato Y*, Ohishi T, Kawada M, Maekawa N, Konnai S, Itai S, Yamada S, Kaneko MK.
(*corresponding author)
The mouse–canine chimeric anti-dog podoplanin antibody P38B exerts antitumor activity in mouse xenograft models
Biochem Biophys Rep., 17:23–26, 2019 (PDF)
2018
43. Kato Y*, Yamada S, Itai S, Kobayashi A, Konnai S, Kaneko MK.
(*corresponding author)
Immunohistochemical detection of sheep podoplanin using an anti-bovine podoplanin monoclonal antibody PMab-44
Monoclon. Antib. Immunodiagn. Immunother., 37(6); 265–268, doi: 10.1089/mab.2018.0036., 2018 (PDF)
42. Kato Y*, Yamada S, Itai S, Kobayashi A, Konnai S, Kaneko MK.
(*corresponding author)
Anti-Horse Podoplanin Monoclonal Antibody PMab-219 is useful for detecting lymphatic endothelial cells by immunohistochemical analysis
Monoclon. Antib. Immunodiagn. Immunother., 37(6); 272–274, https://doi.org/10.1089/mab.2018.0044, 2018
41. Kato Y*, Mizuno T, Yamada S, Nakamura T, Itai S, Yanaka M, Sano M, Kaneko MK.
(*corresponding author)
Establishment of P38Bf, a Core-Fucose-Deficient Mouse-Canine Chimeric Antibody against Dog Podoplanin
Monoclon. Antib. Immunodiagn. Immunother.,37(5):218–223, https://doi.org/10.1089/mab.2018.0035, 2018 (PDF)
40. Yamada S, Itai S, Furusawa Y, Sano M, Nakamura T, Yanaka M, Handa S, Hisamatsu K, Nakamura Y, Fukui M, Harada H, Mizuno T, Sakai Y, Ogasawara S, Murata T, Uchida H, Tahara H, Kaneko MK, Kato Y.*
(*corresponding author)
Detection of tiger podoplanin using the anti-cat podoplanin monoclonal antibody PMab-52
Monoclon. Antib. Immunodiagn. Immunother.,37(5):224–228, https://doi.org/10.1089/mab.2018.0033, 2018 (PDF)
39. Furusawa Y, Yamada S, Itai S, Sano M, Nakamura T, Yanaka M, Handa S, Mizuno T, Maeda K, Fukui M, Harada H, Kaneko MK, Kato Y.*
(*corresponding author)
Establishment of Monoclonal Antibody PMab-202 against Horse Podoplanin
Monoclon. Antib. Immunodiagn. Immunother.,37(5):233–237, https://doi.org/10.1089/mab.2018.0030, 2018 (PDF)
38. Nakano T, Ogasawara S, Tanaka T, Hozumi Y, Yamaki A, Sakane F, Shirai Y, Nakamura T, Yanaka M, Yamada S, Kaneko MK, Kato Y, Goto K.
DgMab-6: Anti-Human DGKgamma Monoclonal Antibody for immunocytochemistry
Monoclon. Antib. Immunodiagn. Immunother.,37(5):233–237, https://doi.org/10.1089/mab.2018.0026, 2018 (PDF)
37. Itai S, Yamada S, Kaneko MK, Sano M, Nakamura T, Yanaka M, Handa S, Hisamatsu K, Nakamura Y, Furusawa Y, Fukui M, Ohishi T, Kawada M, Harada H, Kato Y.*.
(*corresponding author)
Podocalyxin is crucial for the growth of oral squamous cell carcinoma cell line HSC-2
Biochem Biophys Rep., 15: 93-96, https://doi.org/10.1016/j.bbrep.2018.07.008, 2018 (PDF)
36. Furusawa Y, Yamada S, Itai S, Nakamura T, Fukui M, Harada H, Kaneko MK, Kato Y.*
(*corresponding author)
Elucidation of critical epitope of anti-rat podoplanin monoclonal antibody PMab-2
Monoclon. Antib. Immunodiagn. Immunother., 37(4): 188–193, https://doi.org/10.1089/mab.2018.0025, 2018 (PDF)
35. Kaneko MK, Yamada S, Itai S, Furusawa Y, Nakamura T, Yanaka M, Handa S, Hisamatsu K, Nakamura Y, Fukui M, Harada H, Kato Y*.
(*corresponding author)
Epitope mapping of an anti-alpha thalassemia/mental retardation syndrome X-linked
monoclonal antibody AMab-6
Biochem Biophys Rep.,15: 76-80, https://doi.org/10.1016/j.bbrep.2018.07.003, 2018 (PDF)
34. Yamada S, Itai S, Kaneko MK, Konnai S, Kato Y*.
(*corresponding author)
Epitope mapping of anti-mouse podoplanin monoclonal antibody PMab-1
Biochem Biophys Rep., 15:52-56, https://doi.org/10.1016/j.bbrep.2018.07.002, 2018 (PDF)
33. Furusawa Y, Itai S, Yamada S, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope mapping of anti-telomerase reverse transcriptase (TERT) monoclonal antibodies
Monoclon. Antib. Immunodiagn. Immunother., 37(4): 185–187, https://doi.org/10.1089/mab.2018.0019, 2018 (PDF)
32. Itai S, Yamada S, Kaneko MK, Kato Y*.
(*corresponding author)
Determination of critical epitope of PcMab-47 against human podocalyxin
Biochem Biophys Rep.,14: 78–82, https://doi.org/10.1016/j.bbrep.2018.04.003, 2018 (PDF)
31. Kaneko MK, Yamada S, Itai S, Chang YW, Nakamura T, Yanaka M, Kato Y*.
(*corresponding author)
Elucidation of the critical epitope of an anti-EGFR monoclonal antibody EMab-134
Biochem Biophys Rep., 14, 54-57, 2018 (PDF)
30. Yamada Y, Itai S, Nakamura T, Yanaka M, Kaneko MK, Kato Y*.
(*corresponding author)
Detection of high CD44 expression in oral cancers using the novel monoclonal antibody, C44Mab-5
Biochem Biophys Rep.,14, 64-68, 2018 (PDF)
29. Kato Y*, Yamada S, Itai S, Konnai S, Kobayashi A, Kaneko MK.
(*corresponding author)
Detection of alpaca podoplanin by immunohistochemistry using the anti-bovine podoplanin monoclonal antibody PMab-44
Monoclon. Antib. Immunodiagn. Immunother., 37(6); 269–271, doi: 10.1089/mab.2018.0037, 2018 (PDF)
28. Itai S, Ohishi T, Kaneko MK, Yamada S, Abe S, Nakamura T, Yanaka M, Chang YW, Ohba SI, Nishioka Y, Kawada M, Harada H, Kato Y*.
(*corresponding author)
Anti-podocalyxin antibody exerts antitumor effects via antibody-dependent cellular cytotoxicity in mouse xenograft models of oral squamous cell carcinoma.
Oncotarget, 9(32):22480-22497, https://doi.org/10.18632/oncotarget.25132, 2018 (PDF)
27. Kaneko MK, Itai S, Yamada S, Kato Y*.
(*corresponding author)
47-mG2a: A Mouse IgG2a-type of PcMab-47 Useful for Detecting Podocalyxin in Esophageal Cancers by Immunohistochemistry
Monoclon. Antib. Immunodiagn. Immunother., doi: 10.1089/mab.2018.0003., 37(3),158–161, 2018 (PDF)
26. Yamada S, Itai S, Nakamura T, Yanaka M, Chang YW, Suzuki H, Kaneko MK, Kato Y.*.
(*corresponding author)
Monoclonal Antibody L1Mab-13 Detected PD-L1 in Lung Cancers.
Monoclon. Antib. Immunodiagn. Immunother., doi: 10.1089/mab.2018.0004, , 37(2), 110-115, 2018 (PDF)
25. Yamada S, Kaneko MK, Itai S, Chang YW, Nakamura T, Yanaka M, Ogasawara S, Murata T, Uchida H, Tahara H, Harada H, Kato Y.*.
(*corresponding author)
Epitope Mapping of Monoclonal Antibody PMab-48 against Dog Podoplanin.
Monoclon. Antib. Immunodiagn. Immunother., doi: 10.1089/mab.2018.0006, 37(3),162–165, 2018 (PDF)
24. Yamada S, Itai S, Kaneko MK, Kato Y*.
(*corresponding author)
Anti-Podocalyxin Monoclonal Antibody 47-mG2a Detects Lung Cancers by Immunohistochemistry Analyses.
Monoclon. Antib. Immunodiagn. Immunother., 37(2), https://doi.org/10.1089/mab.2018.0002, 91-94, 2018 (PDF)
23. Yamada S, Itai S, Kaneko MK, Kato Y*.
(*corresponding author)
Detection of high PD-L1 expression in oral cancers by a novel monoclonal antibody L1Mab-4
Biochem Biophys Rep., 13, 123–128, 2018 (PDF)
22. Chang YW, Kaneko MK, Yamada S, Kato Y.*
(*corresponding author)
Epitope Mapping of Monoclonal Antibody PMab-52 Against Cat Podoplanin.
Monoclon. Antib. Immunodiagn. Immunother., https://doi.org/10.1089/mab.2017.0067, 37(2): 95–99, 2018 (PDF)
21. Kaneko MK, Yamada, S, Itai S, Kato Y*.
(*corresponding author)
Development of an Anti-HER2 Monoclonal Antibody (H2Mab-139) Against Colon Cancer.
Monoclon. Antib. Immunodiagn. Immunother., 37(1): 59-62, 2018 (PDF)
20. Suzuki T, Takakubo Y, Oki H, Liu X, Honma R, Naganuma Y, Goodman S, Kaneko MK, Kato Y, Takagi M.
Immunohistochemical Analysis of Inflammatory Rheumatoid Synovial Tissues Using Anti-Human Podoplanin Monoclonal Antibody Panel.
Monoclon. Antib. Immunodiagn. Immunother., 37(1): 12-19, 2018 (PDF)
19. Yamada S, Itai S, Kaneko MK, Kato Y*.
(*corresponding author)
PMab-48 recognizes canine podoplanin of lymphatic endothelial cells.
Monoclon. Antib. Immunodiagn. Immunother., 37(1): 63-66, 2018 (PDF)
2017
18. Yamada S, Itai S, Nakamura T, Chang YW, Harada H, Suzuki H, Kaneko MK, Kato Y*.
(*corresponding author)
Establishment of H2Mab-119, an Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody, Against Pancreatic Cancer.
Monoclon. Antib. Immunodiagn. Immunother.,36(6): 287-290, 2017 (PDF)
17. Chang YW, Yamada S, Kaneko MK, Kato Y*.
(*corresponding author)
Epitope Mapping of Monoclonal Antibody PMab-38 Against Dog Podoplanin.
Monoclon. Antib. Immunodiagn. Immunother., 36(6): 291-295, 2017 (PDF)
16. Itai S, Yamada S, Kaneko MK, Harada H, Kagawa Y, Konnai S, Kato Y*.
(*corresponding author)
Expression of cat podoplanin in feline squamous cell carcinomas.
Monoclon. Antib. Immunodiagn. Immunother.,36(6): 243-250, 2017 (PDF)
15. Itai S, Yamada S, Kaneko MK, Chang YW, Harada, H, Kato Y*.
(*corresponding author)
Establishment of EMab-134, a sensitive and specific anti-epidermal growth factor receptor monoclonal antibody for detecting squamous cell carcinoma cells of the oral cavity.
Monoclon. Antib. Immunodiagn. Immunother., 36(6): 272-281, 2017 (PDF)
14. Itai S, Fujii Y, Nakamura T, Chang YW, Yanaka M, Saidoh N, Handa S, Suzuki H, Harada H, Yamada S, Kaneko MK, Kato Y*.
(*corresponding author)
Establishment of CMab-43, a Sensitive and Specific Anti-CD133 Monoclonal Antibody, for Immunohistochemistry.
Monoclon. Antib. Immunodiagn. Immunother., 36(5):231-235, 2017
13. Itai S, Kaneko MK, Fujii Y, Yamada S, Nakamura T, Yanaka M, Saidoh N, Handa S, Chang Yao-Wen, Suzuki H, Harada H, Kato Y.
(*corresponding author)
Development of EMab-51, a Sensitive and Specific Anti-EGFR Monoclonal Antibody in Western Blot and Immunohistochemistry.
Monoclon. Antib. Immunodiagn. Immunother., 36(5):214-219, 2017
12. Itai S, Yamada S, Kaneko MK, Harada H, Kato Y.
(*corresponding author)
Immunohistochemical Analysis Using Anti-Podocalyxin Monoclonal Antibody PcMab-47 Demonstrates Podocalyxin Expression in Oral Squamous Cell Carcinoma Cells.
Monoclon. Antib. Immunodiagn. Immunother., 36(5):220-223, 2017
11. Yamada S, Itai S, Nakamura T, Yanaka M, Saidoh N, Chang YW, Handa S, Harada H, Kagawa Y, Ichii O, Konnai S, Kaneko MK, Kato Y.
PMab-52: Specific and Sensitive Monoclonal Antibody against Cat Podoplanin for Immunohistochemistry.
Monoclon. Antib. Immunodiagn. Immunother., 36(5):224-230, 2017
10. Itai S, Fujii Y, Kaneko MK, Yamada S, Nakamura T, Yanaka M, Saidoh N, Chang YW, Handa S, Takahashi M, Suzuki H, Harada H, Kato Y.
H2Mab-77 is a sensitive and specific anti-HER2 monoclonal antibody against breast cancer.
Monoclon. Antib. Immunodiagn. Immunother., 36(4): 143-148, 2017
9. Kaneko MK, Kunita A, Yamada S, Nakamura T, Yanaka M, Saidoh N, Chang YW, Handa S, Ogasawara S, Ohishi T, Abe S, Itai S, Harada H, Kawada M, Nishioka Y, Fukayama M, Kato Y.*
Anti-Podocalyxin Antibody chPcMab-47 Exerts Antitumor Activity in Mouse Xenograft Models of Colorectal Adenocarcinomas.
Monoclon. Antib. Immunodiagn. Immunother., 36(4): 157-162, 2017
8. Yamada S, Honma R, Kaneko MK, Nakamura T, Yanaka M, Saidoh N, Takagi M, Konnai S, Kato Y.*
(*corresponding author)
Characterization of Anti-bovine Podoplanin Monoclonal Antibody PMab-44
Monoclon. Antib. Immunodiagn. Immunother., 36(3): 129-134, 2017
7. Kaneko MK, Nakamura T, Kunita A, Fukayama M, Abe S, Nishioka Y, Yamada S, Yanaka M, Saidoh N, Yoshida K, Fujii Y, Ogasawara S, Kato Y
(*corresponding author)
ChLpMab-23: Cancer-specific Human-Mouse Chimeric Anti-podoplanin Antibody Exhibits Antitumor Activity via Antibody-Dependent Cellular Cytotoxicity
Monoclon. Antib. Immunodiagn. Immunother., 36(3): 104-112, 2017
6. Ogasawara S, Kaneko MK, Yamada S, Honma R, Nakamura T, Saidoh N, Yanaka M, Yoshida K, Fujii Y, Kato Y.*
PcMab-47: Novel Anti-human Podocalyxin Monoclonal Antibody for Immunohistochemistry
Monoclon. Antib. Immunodiagn. Immunother., DOI: 36(2): 50-56, 2017
5. Yamada S, Ogasawara S, Kaneko MK, Kato Y.*
(*corresponding author)
LpMab-23: A Cancer-Specific Monoclonal Antibody against Human Podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 36(2): 72-76, 2017
4. Yamada S, Kaneko MK, Nakamura T, Ichii O, Konnai S, Kato Y.*
(*corresponding author)
Development of mPMab-1, a Mouse-Rat Chimeric Antibody against Mouse Podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 36(2): 77-79, 2017
3. Kaneko MK, Yamada S, Nakamura T, Abe S, Nishioka Y, Kunita A, Fukayama M, Fujii Y, Ogasawara S, Kato Y*
(*corresponding author)
Antitumor activity of chLpMab-2, a human-mouse chimeric cancer-specific antihuman podoplanin antibody, via antibody-dependent cellular cytotoxicity
Cancer Med., ,6(4): 768-777, 2017
2. Kaneko MK*, Abe S, Ogasawara S, Fujii Y, Yamada S, Murata T, Uchida H, Tahara H, Nishioka Y, Kato Y*.
(*corresponding author)
Chimeric Anti-human Podoplanin Antibody NZ-12 of Lambda Light Chain Exerts Higher Antibody-dependent Cellular Cytotoxicity and Complement-dependent Cytotoxicity Compared with NZ-8 of Kappa Light Chain.
Monoclon. Antib. Immunodiagn. Immunother., 36(1): 25-29, 2017
1. Kato Y*, Kunita A, Fukayama M, Abe S, Nishioka Y, Uchida H, Tahara H, Yamada S, Yanaka M, Nakamura T, Saidoh N, Yoshida K, Fujii Y, Honma R, Takagi M, Ogasawara S, Murata T, Kaneko MK*
(*corresponding author)
Anti-Glycopeptide Mouse Monoclonal Antibody LpMab-21 Exerts Antitumor Activity Against Human Podoplanin via Antibody-Dependent Cellular Cytotoxicity and Complement-Dependent Cytotoxicity
Monoclon. Antib. Immunodiagn. Immunother., 36(1): 20-24, 2017
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