＊in press ~ online掲載論文については、抗体創薬学分野の業績参照。

2024

97. Tanaka T, Suzuki H, Ohishi T, Kaneko MK, Kato Y.
A Cancer-Specific anti-Podoplanin Monoclonal Antibody, PMab-117-mG2a Exerted Antitumor Activities in Human Tumor Xenograft Models
Cells, 13(22), 1833; https://doi.org/10.3390/cells13221833, 2024 (PDF; preprint)


96. Hirose M, Suzuki H, Ubukata R, Tanaka T, Kaneko MK, Kato Y.
Development of specific anti-mouse atypical chemokine receptor 4 monoclonal antibodies
Biochem Biophys Rep, 40, 101824, https://doi.org/10.1016/j.bbrep.2024.101824, 2024 (PDF; preprint)


95. Ishikawa K, Suzuki H, Ohishi T, Nakamura T, Yanaka M, Li G, Tanaka T, Kawada M, Kaneko MK, Ohkoshi A, Katori Y, Kato Y.
Antitumor activities of defucosylated anti-CD44 monoclonal antibodies in mouse xenograft models of esophageal cancer
Oncology reports, 52(5), 147, https://doi.org/10.3892/or.2024.8806, (PDF; preprint)


94. Ishikawa K, Suzuki H, Ohishi T, Li G, Tanaka T, Kawada M, Ohkoshi A, Kaneko MK, Katori Y, Kato Y.
Anti-CD44 variant 10 monoclonal antibody exerts antitumor activity in mouse xenograft models of oral squamous cell carcinomas
Int. J. Mol. Sci., 25(17), 9190; https://doi.org/10.3390/ijms25179190, 2024 (PDF; preprint)


93. Ubukata R, Suzuki H, Tanaka T, Li G, Kaneko MK, Kato Y.
Development of Sensitive Anti-Mouse CCR5 Monoclonal Antibodies using the N-terminal peptide immunization
Monoclon. Antib. Immunodiagn. Immunother., 43(4), 112-118, https://doi.org/10.1089/mab.2024.0009, 2024 (PDF)

92. Suzuki H, Tanaka T, Li G, Ouchida T, Kaneko MK, Kato Y.
Development of a Sensitive Anti-Mouse CCR5 Monoclonal Antibody for Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother., 43(4), 96-100, https://doi.org/10.1089/mab.2024.0004, 2024 (PDF; preprint)

91. Kobayashi H, Suzuki H, Tanaka T, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-Mouse CCR8 Monoclonal Antibody C8Mab-2 using flow cytometry
Monoclon. Antib. Immunodiagn. Immunother., 43(4), 101-107, https://doi.org/10.1089/mab.2024.0002, 2024 (PDF; preprint)

90. Suzuki H, Ohishi T, Tanaka T, Kaneko MK, Kato Y.
Anti‐HER2 cancer‐specific mAb, H2Mab‐250‐hG1 possesses higher complement‐dependent cytotoxicity than trastuzumab
Int. J. Mol. Sci., 25(15), 8386; https://doi.org/10.3390/ijms25158386, 2024 (PDF; preprint)


89. Suzuki H, Tawara M, Hirayama A, Goto N, Tanaka T, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-CD44v4 Monoclonal Antibody (C44Mab-108) using Enzyme-Linked Immunosorbent Assay
Monoclon. Antib. Immunodiagn. Immunother., 43(3), 85-89, https://doi.org/10.1089/mab.2023.0022, 2024 (PDF; preprint)

88. Ouchida T, Isoda Y., Tanaka T, Kaneko MK, Suzuki H, Kato Y.
Cx3Mab-4: a Novel Anti-mouse CXCR3 Monoclonal Antibody for Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother., 43(3), 90-95, https://doi.org/10.1089/mab.2023.0024, 2024 (PDF;preprint)

87. Machitani M, Nomura A, Yamashita T, Yasukawa M, Ueki S, Fujita KI, Ueno T, Yamashita A, Tanzawa Y, Watanabe M, Taniguchi T, Saitoh N, Kaneko S, Kato Y, Mano H, Masutomi K.
Maintenance of R-loop structures by phosphorylated hTERT preserves genome integrity
Nat Cell Biol, 26(6):932-945, 10.1038/s41556-024-01427-6, 2024 (PDF)

86. Arimori T, Mihara E, Suzuki H, Ohishi T, Tanaka T, Kaneko MK, Takagi J, Kato Y.
Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies
Structure, 32(5),536-549, https://doi.org/10.1016/j.str.2024.02.007, 2024 (PDF)


85. Li G, Tanaka T, Suzuki H, Kaneko MK, Kato Y.
Cx1Mab-1: A Novel Anti-mouse CXCR1 Monoclonal Antibody for Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother.,43(2), 59-66, DOI: 10.20944/preprints202311.0501.v2, 2023 (PDF;preprint)

84. Ouchida T, Li G, Suzuki H, Yanaka M, Nakamura T, Handa S, Tanaka T, Kaneko MK, Kato Y.
PMab-314: An Anti-Giant Panda Podoplanin Monoclonal Antibody
Monoclon. Antib. Immunodiagn. Immunother.,43(2), 53-58, doi:10.1089/mab.2024.0003, 2024 (PDF)

83. Kaneko MK, Suzuki H, Kato Y.
Establishment of a novel cancer-specific anti-HER2 monoclonal antibody H2Mab-250/H2CasMab-2 for breast cancers
Monoclon. Antib. Immunodiagn. Immunother.,43(2), 35-43, DOI: 10.1089/mab.2023.0033, 2024 (PDF;online;preprint)

82. Ouchida T, Isoda Y, Nakamura T, Yanaka M, Tanaka T, Handa S, Kaneko MK, Suzuki H, Kato Y.
Establishment of a Novel Anti-Mouse CCR1 Monoclonal Antibody C1Mab-6
Monoclon. Antib. Immunodiagn. Immunother.,43(2), 67-74, https://doi.org/10.1089/mab.2023.0032, 2024 (PDF;preprint)

81. Okada Y, Suzuki H, Tanaka T, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-Mouse CD39 Monoclonal Antibody using PA Scanning and RIEDL Scanning
Monoclon. Antib. Immunodiagn. Immunother.,43(2), 44-52, https://doi.org/10.1089/mab.2023.0029, 2024 (PDF;preprint)

80. Inoue T, Yamamoto Y, Sato K, Nakamura Y, Shimizu Y, Ogawa M, Onodera T, Takahashi Y, Wakita T, Kaneko MK, Fukasawa M, Kato Y, Noguchi K.
Overcoming antibody-resistant SARS-CoV-2 variants with bispecific antibodies constructed using non-neutralizing antibodies
iScience,27(4),109363, DOI:https://doi.org/10.1016/j.isci.2024.109363, 2024 (PDF)

79. Ouchida T, Suzuki H, Tanaka T, Kaneko MK, Kato Y.
Establishment of anti-dog PD-L1 monoclonal antibodies for immunohistochemistry
Monoclon. Antib. Immunodiagn. Immunother., 43(1), 17–23, https://doi.org/10.1089/mab.2023.0014, 2024 (PDF; preprint)

78. Okada Y, Suzuki H, Kaneko MK, Kato Y.
Development of a Sensitive Anti-Mouse CD39 Monoclonal Antibody (C39Mab-1) for Flow Cytometry and Western Blot Anal-yses
Monoclon. Antib. Immunodiagn. Immunother., 43(1), 24–31, https://doi.org/10.1089/mab.2023.0016, 2024 (PDF; preprint)

77. Ouchida T, Suzuki H, Tanaka T, Kaneko MK, Kato Y.
Cx4Mab-1: a Novel Anti-mouse CXCR4 Monoclonal Antibody for Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother., 43(1), 10–16, DOI: 10.1089/mab.2023.0023, 2024 (PDF;preprint)

76. Yoneda H, Mitsuhashi A, Yoshida A, Ogino H, Itakura S, Nguyen NT, Nokihara H, Sato S, Shinohara T, Hanibuchi M, Abe S, Kaneko MK, Kato Y, Nishioka Y.
Anti-podoplanin antibody enhances the antitumor effects of CTLA-4 blockade against malignant mesothelioma by natural killer cells
Cancer Sci.,115(2), https://doi.org/10.1111/cas.16046, 2023 (PDF)

75. Kaneko MK, Suzuki H, Ohishi T, Nakamura T, Tanaka T, Kato Y.
A Cancer-specific Monoclonal Antibody against HER2 Exerts Antitumor Activities in Human Breast Cancer Xenograft Models
Int. J. Mol. Sci., 25(3), 1941; https://doi.org/10.3390/ijms25031941, 2024 (PDF)

74. Tanaka T, Suzuki H, Ohishi T, Kaneko MK, Kato Y.
Antitumor activities against breast cancers by an afucosylated anti-HER2 monoclonal antibody H2Mab-77-mG2a-f
Cancer Sci., 115(1), 298-309, https://doi.org/10.1111/cas.16008, 2024 (PDF; preprint)

73. Suzuki H, Ohishi T, Tanaka T Kaneko MK, Kato Y.
A Cancer-Specific Monoclonal Antibody against Podocalyxin Exerted Antitumor Activities in Pancreatic Cancer Xenografts
Int. J. Mol. Sci., 25, 161. https://doi.org/10.3390/ijms25010161, 2024 (PDF; preprint)



2023

72. Isoda Y, Kaneko MK, Tanaka T, Suzuki H, Kato Y.
Epitope Mapping of an Anti-Ferret Podoplanin Monoclonal Antibody using the PA Tag-Substituted Analysis
Monoclon. Antib. Immunodiagn. Immunother., 42(6), 189–193, DOI: 10.1089/mab.2023.0026, 2023 (PDF; preprint)

71. Ouchida T, Tanaka T, Suzuki H, Kaneko MK, Kato Y.
PMab-301: An Anti-Giraffe Podoplanin Monoclonal Antibody for Immunohistochemistry
Monoclon. Antib. Immunodiagn. Immunother., 42(6), 209–215, https://doi.org/10.1089/mab.2023.0020, 2023 (PDF; preprint)

70. Suzuki H, Tanaka T, Kudo Y, Tawara M, Hirayama A, Kaneko MK, Kato Y.
A Rat Anti-Mouse CD39 Monoclonal Antibody for flow cytometry
Monoclon. Antib. Immunodiagn. Immunother., 42(6), 203–208, DOI: 10.1089/mab.2023.0018, 2023 (PDF; preprint)

69. Yamada K, Shioya R, Nishino K, Furihata H, Hijikata A, Kaneko MK, Kato Y, Shirai T, Kosako H, Sawasaki T.
Proximity extracellular protein-protein interaction analysis of EGFR using AirID-conjugated fragment of antigen binding
Nat Commun, 14(1):8301. doi: 10.1038/s41467-023-43931-7, 2023 (PDF)

68. Shinada M, Kato D, Motegi T, Tsuboi M, Ikeda N, Aoki S, Iguchi T, Li T, Kodera Y, Ota R, Hashimoto Y, Takahashi Y, Chambers J, Uchida K, Kato Y, Nishimura R, Nakagawa T.
Podoplanin drives amoeboid invasion in canine and human mucosal melanoma
Mol Cancer Res., 21 (11): 1205–1219, https://doi.org/10.1158/1541-7786.MCR-22-0929, 2023 (PDF)

67. Nanamiya R, Suzuki H, Kaneko MK, Kato Y.
Development of an Anti−EphB4 Monoclonal Antibody for Multiple Applications against Breast Cancers
Monoclon. Antib. Immunodiagn. Immunother.,42(5), 153–156, https://doi.org/10.1089/mab.2023.0015, 2023 (PDF; preprint)

66. Suzuki H, Ohishi T, Kaneko MK, Kato Y.
Humanized and defucosylated antibody against Podoplanin (humLpMab-23-f) exerted antitumor activities in human tumor xenograft models
Cancers, 15(20), 5080; https://doi.org/10.3390/cancers15205080, 2023 (PDF)

65. Shinada M, Kato D, Tsuboi M, Ikeda N, Aoki S, Iguchi T, Li T, Kodera Y, Ota R, Koseki S, Shibahara H, Takahashi Y, Hashimoto Y, Chambers J, Uchida K, Noguchi S, Kato Y, Nishimura R, Nakagawa T.
Podoplanin promotes cell proliferation, survival, and migration of canine non-tonsillar squamous cell carcinoma
J Vet Med Sci.,85(10): 1068–1073, https://doi.org/10.1292/jvms.23-0062, 2023 (PDF)

64. Ishida K, ‪Yagi‬ H, Kato Y, Morita E.
N-linked glycosylation of Flavivirus E protein contributes to viral particle formation
PLoS Pathog., 19(10):e1011681. doi: 10.1371/journal.ppat.1011681, 2023

63. Maekawa N, Konnai S, Hosoya K, Kim S, Kinoshita R, Deguchi T, Owaki R, Tachibana Y, Yokokawa M, Takeuchi H, Kagawa Y, Takagi S, Ohta H, Kato Y, Yamamoto S, Yamamoto K, Suzuki Y, Okagawa Y, Murata S, Ohashi K.
Safety and clinical efficacy of an anti-PD-L1 antibody (c4G12) in dogs with advanced malignant tumours
PLoS One, 18(10): e0291727, https://doi.org/10.1371/journal.pone.0291727, 2023 (PDF)

62. Okagawa T, Konnai S, Goto S, Sajiki Y, Ganbaatar O, Watari K, Nakamura H, Wang CX, Tachibana T, Kato Y, Kameda Y, Kohara J, Terasaki N, Kubota M, Takeda A, Takahashi H, Suzuki Y, Maekawa N, Murata S, Ohashi K.
Development of a high-affinity anti-bovine PD-1 rabbit–bovine chimeric antibody using an efficient selection and large production system
Vet Res., 54(1):82, doi: 10.1186/s13567-023-01213-6.2023 (PDF)

61. Suzuki H, Ohishi T, Nanamiya R, Kawada M, Kaneko MK, Kato Y.
Defucosylated Monoclonal Antibody (H2Mab-139-mG2a-f) Exerted Antitumor Activities in Mouse Xenograft Models of Breast Cancers against Human Epidermal Growth Factor Receptor 2
Curr. Issues Mol. Biol., 45(10), 7734-7748; https://doi.org/10.3390/cimb45100488, 2023　(PDF)

60. Tanaka T, Kitamura K, Suzuki H, Kaneko MK, Kato Y.
Establishment of a Novel Anti-Human CCR6 Monoclonal Antibody C6Mab-19 with the High Binding Affinity in Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother., 42(4), 117–124, https://doi.org/10.1089/mab.2023.0004, 2023 (preprint; PDF)

59. Ouchida T, Suzuki H, Tanaka T, Kaneko MK, Kato Y.
Development of Highly Sensitive Anti-Mouse HER2 Monoclonal Antibodies for Flow Cytometry
Int. J. Transl. Med., 3(3), 310-320; 2023 (PDF)

58. Han BB, Watanabe S, Nomura N, Liu K, Uemura T, Inoue M, Tsutsumi A, Fujita H, Kinoshita K, Kato Y, Iwata S, Kikkawa M, Inaba K.
Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn2+ uptake into the Golgi apparatus
Nat comm., 14, 4770, doi: https://doi.org/10.1101/2022.03.23.485435, 2023 (PDF)

57. Suzuki H, Goto N, Tanaka T, Ouchida T, Kaneko MK, Kato Y.
Development of a Novel Anti-CD44 Variant 8 Monoclonal Antibody C44Mab-94 against Gastric Carcinomas
antibodies, 12(3), 45; https://doi.org/10.3390/antib12030045, 2023 (PDF)

56. Ishikawa K, Suzuki H, Kaneko MK, Kato Y.
A Novel Anti-CD44 Variant 10 Monoclonal Antibody is Useful for Immunohistochemical Analysis against Oral Squamous cell carcinomas
Curr. Issues Mol. Biol., 45(7), 5248-5262; https://doi.org/10.3390/cimb45070333, 2023 (PDF)

55. Goto N, Suzuki H, Tanaka T, Ishikawa K, Ouchida T, Kaneko MK, Kato Y.
EMab-300 Detects Mouse Epidermal Growth Factor Receptor-Expressing Cancer Cell Lines in Flow Cytometry
antibodies, 12(3), 42, doi: 10.20944/preprints202305.0641.v1, 2023 (PDF)

54. Deguchi T, Maekawa N, Konnai S, Owaki R, Hosoya K, Morishita K, Nakamura M, Okagawa T, Takeuchi H, Kim S, Kinoshita R, Tachibana Y, Ykokawa M, Takagi S, Kato Y, Suzuki Y, Murata S, Ohashi K.
Enhanced Systemic Antitumour Immunity by Hypofractionated Radiotherapy and Anti-PD-L1 Therapy in Dogs with Pulmonary Metastatic Oral Malignant Melanoma
Cancers, 15(11), 3013; https://doi.org/10.3390/cancers15113013, 2023 (PDF)

53. Murate M, Yokoyama N, Tomishige N, Richert L, Humbert N, Pollet B, Makino A, Kono N, Mauri L, Aoki J, Sako Y, Sonnino S, Komura N, Ando H, Kaneko MK, Kato Y, Inamori KI, Inokuchi JI, Mély Y, Iwabuchi K, Kobayashi T.
Cell density-dependent membrane distribution of ganglioside GM3 in melanoma cells
Cell. Mol. Life Sci., 80, 167, https://doi.org/10.1007/s00018-023-04813-9, 2023 (Research Square)

52. Tiyamanee W, Konnai S, Okagawa T, Nojima Y, Ganbaatar O, Maekawa N, Hasebe R, Kagawa Y, Kato Y, Suzuki Y, Murata S, Ohashi K.
Molecular characterization of immunoinhibitory factors PD-1/PD-L1 in sheep
Vet Immunol Immunopathol., 261, 110609, https://doi.org/10.1016/j.vetimm.2023.110609, 2023 (PDF)

51. Adachi Y, Kaneko MK, Kato Y, Nogi T.
Recombinant production of antibody antigen-binding fragments with an N-terminal human growth hormone tag in mammalian cells
Protein Expr Purif., 208–209, 106289, https://doi.org/10.1016/j.pep.2023.106289, 2023 (PDF)

50. Suzuki H, Kitamura K, Goto N, Ishikawa K, Ouchida T, Tanaka T, Kaneko MK, Kato Y.
A Novel Anti-CD44 Variant 3 Monoclonal Antibody C44Mab-6 was Established for Multiple Applications
Int. J. Mol. Sci., 24(9), 8411; https://doi.org/10.3390/ijms24098411, 2023 (PDF)

49. Tanaka T, Tawara M, Suzuki H, Kaneko MK, Kato Y.
Identification of the Binding Epitope of an Anti-Mouse CCR6 Monoclonal Antibody (C6Mab-13) Using 1× Alanine Scanning
antibodies, 12(2), 32; https://doi.org/10.3390/antib12020032, 2023 (PDF)

48. Kudo Y, Suzuki H, Tanaka T, Kaneko MK, Kato Y.
Development of a Novel Anti-CD44 Variant 5 Monoclonal Antibody C44Mab-3 for Multiple Applications against Pancreatic Carcinomas
antibodies, 12(2), 31, https://doi.org/10.3390/antib12020031, 2023 (PDF)

47. Isoda Y, Tanaka Y, Suzuki H, Asano T, Kitamura K, Kudo Y, Ejima R, Ozawa K, Yoshikawa T, Kaneko MK, Kato Y.
Epitope Mapping of the Novel Anti-human CCR9 Monoclonal Antibody (C9Mab-11) by 2 × Alanine Scanning
Monoclon. Antib. Immunodiagn. Immunother., 42(2), 73–76, https://doi.org/10.1089/mab.2022.0035, 2023 (PDF)

46. Tateyama N, Asano T, Tanaka T, Isoda T, Okada Y, Kobayashi H, Li G, Nanamiya R, Yoshikawa T, Kaneko MK, Suzuki H, Kato Y.
Epitope Mapping of Anti-mouse CCR3 Monoclonal Antibodies (C3Mab-6 and C3Mab-7)
Monoclon. Antib. Immunodiagn. Immunother., 42(2), 68–72, https://doi.org/10.1089/mab.2022.0034, 2023 (PDF)

45. Nishibori S, Kaneko MK, Nakagawa T, Nishigaki K, Kato Y, Igase M, Mizuno T.
Development of anti-feline PD-1 antibody and its functional analysis
Sci Rep., 13, 6420,doi: 10.1038/s41598-023-31543-6, 2023 (PDF)

44. Tawara M, Suzuki H, Goto N, Tanaka T, Kaneko MK, Kato Y.
A Novel Anti-CD44 Variant 9 Monoclonal Antibody C44Mab-1 was Developed for Immunohistochemical Analyses Against Colorectal Cancers
Curr. Issues Mol. Biol., 45(4), 3658-3673, doi: 10.3390/cimb45040238, 2023 (PDF)

43. Suzuki H, Ozawa K, Tanaka T, Kaneko MK, Kato Y.
Development of a Novel Anti-CD44 Variant 7/8 Monoclonal Antibody C44Mab-34 for Multiple Applications against Oral Carcinomas
Biomedicines, 11(4), 1099; https://doi.org/10.3390/biomedicines11041099, 2023 (PDF)

42. Li G, Suzuki H, Tanaka T, Asano T, Yoshikawa T, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-EpCAM Monoclonal Antibody (EpMab-37) using the Alanine Scanning Method
Monoclon. Antib. Immunodiagn. Immunother., 42(1), 41–47, doi: 10.1089/mab.2022.0031, 2023 (PDF)

41. Kobayashi H, Asano T, Suzuki H, Tanaka T, Yoshikawa T, Kaneko MK, Kato Y.
Establishment of a Sensitive Monoclonal Antibody against Mouse CCR9 (C9Mab-24) for Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother., 42(1), 15–21, https://doi.org/10.1089/mab.2022.0032, 2022 (PDF)

40. Nanamiya R, Ohishi T, Suzuki H, Mizuno T, Yoshikawa T, Asano T, Tanaka T, Kaneko MK, Kato Y.
Defucosylated mouse-dog chimeric anti-HER2 monoclonal antibody (H77Bf) exerts antitumor activities in mouse xenograft models of canine osteosarcoma
Monoclon. Antib. Immunodiagn. Immunother., 42(1), 27–33, doi:10.1089/mab.2022.0022, 2022 (PDF)

39. Suzuki H, Asano T, Ohishi T, Yoshikawa T, Suzuki H, Mizuno T, Tanaka T, Kawada M, Kaneko MK, Kato Y.
Antitumor Activities in Mouse Xenograft Models of Canine Fibroblastic Tumor by Defucosylated Mouse-Dog Chimeric Anti-HER2 Monoclonal Antibody (H77Bf)
Monoclon. Antib. Immunodiagn. Immunother., 42(1), 34–40, doi: 10.1089/mab.2022.0023, 2022 (PDF)

38. Isoda Y, Tanaka T, Suzuki H, Asano T, Yoshikawa T, Kitamura K, Kudo Y, Ejima R, Ozawa K, Kaneko MK, Kato Y.
Epitope Mapping using the Cell-Based 2×Alanine Substitution Method about the Anti-mouse CXCR6 Monoclonal Antibody, Cx6Mab-1
Monoclon. Antib. Immunodiagn. Immunother., 42(1), 22–26, doi: 10.1089/mab.2022.0029, 2022 (PDF)

37. Okagawa T, Konnai S, Nakamura H, Ganbaatar O, Sajiki Y, Watari K, Noda H, Honma M, Kato Y, Suzuki Y, Maekawa N, Murata S, Ohashi K.
Enhancement of Vaccine-Induced T-Cell Responses by PD-L1 Blockade in Calves
Vaccines, 11(3), 559; https://doi.org/10.3390/vaccines11030559, 2023 (PDF)

36. Suzuki H, Tanaka T, Goto N, Kaneko MK, Kato Y.
Development of a novel anti-CD44 variant 4 monoclonal antibody C44Mab-108 for immunohistochemistry
Curr. Issues Mol. Biol., 45(3), 1875-1888; https://doi.org/10.3390/cimb45030121, 2023 (PDF)

35. Ejima R, Suzuki H, Tanaka T, Asano T, Kaneko MK, Kato Y.
Development of a Novel Anti-CD44 variant 6 Monoclonal Antibody C44Mab-9 for Multiple Applications against Colorectal Carcinomas
Int. J. Mol. Sci., 24(4), 4007; https://doi.org/10.3390/ijms24044007, 2023 (PDF)

34. Nakamura H, Konnai S, Okagawa T, Maekawa N, Sajiki Y, Watari K, Kamitani K, Saito M, Kato Y, Suzuki Y, Murata S, Ohashi K.
Combined immune checkpoint blockade enhances antiviral immunity against bovine leukemia virus
J Virol., 97(1), e0143022., doi: 10.1128/jvi.01430-22., 2023

33. Kobayashi H, Asano T, Tanaka T, Suzuki H, Kaneko MK, Kato Y.
Determination of the Binding Epitope of an Anti-mouse CCR9 Monoclonal Antibody (C9Mab-24) using the 1 × alanine and 2 × alanine-substitution Method
antibodies, 12(1), 11; https://doi.org/10.3390/antib12010011, 2023 (PDF)

32. Maekawa N, Konnai S, Asano Y, Otsuka T, Aoki E, Takeuchi H, Kato Y, Kaneko MK, Yamada S, Kagawa Y, Nishimura M, Takagi S, Deguchi T, Ohta H, Nakagawa T, Suzuki Y, Okagawa T, Murata S, Ohashi K.
Molecular characterization of feline immune checkpoint molecules and establishment of PD-L1 immunohistochemistry for feline tumors
PLoS One, 18(1):e0281143. doi: 10.1371/journal.pone.0281143, 2023 (PDF)

31. Li G, Suzuki H, Ohishi T, Asano T, Tanaka T, Yanaka M, Nakamura T, Yoshikawa T, Kawada M, Kaneko MK, Kato Y.
Antitumor activities by a defucosylated anti-EpCAM monoclonal antibody in colorectal carcinoma xenograft models
Int J Mol Med, 51(2), 18, https://doi.org/10.3892/ijmm.2023.5221, 2023 (PDF)

30. Ohishi T, Kaneko MK, Yoshida Y, Takashima A, Kato Y, Kawada M.
Current targeted therapy for metastatic colorectal cancer
Int. J. Mol. Sci. , 24(2), 1702; https://doi.org/10.3390/ijms24021702, 2023 (PDF)

2022

29. Asano T, Tanaka T, Suzuki H, Li G, Nanamiya R, Tateyama N, Isoda Y, Okada Y, Kobayashi H, Yoshikawa T, Kaneko MK, Kato Y.
Development of a Novel Anti-Mouse CCR6 Monoclonal Antibody (C6Mab-13) by N-Terminal Peptide Immunization
Monoclon. Antib. Immunodiagn. Immunother., 41(6), 343–349, doi: 10.1089/mab.2022.0021, 2022 (PDF)

28. Tanaka T, Suzuki H, Asano T, Li G, Nanamiya R, Tateyama N, Isoda Y, Okada Y, Kobayashi H, Yoshikawa T, Kaneko MK, Kato Y.
Epitope mapping of an Anti-Mouse CCR2 Monoclonal Antibody (C2Mab-6) using Enzyme-Linked Immunosorbent Assay
Monoclon. Antib. Immunodiagn. Immunother., 41(6), 339–342, doi:10.1089/mab.2022.0020, 2022 (PDF)

27. Saito M, Suzuki H, Tanaka T, Asano T, Kaneko MK, Kato Y.
Development of an Anti-Mouse CCR8 Monoclonal Antibody (C8Mab-1) for Flow cytometry and Immunocytochemistry
Monoclon. Antib. Immunodiagn. Immunother., 41(6), 333–338, https://doi.org/10.1089/mab.2021.0069, 2022 (PDF)

26. Kawabata H, Ohishi T, Suzuki H, Asano T, Kawada M, Suzuki H, Kaneko MK, Kato Y.
A Defucosylated Mouse Anti-CD10 Monoclonal Antibody (31-mG2a-f) Exerts Antitumor Activity in a Mouse Xenograft Model of Renal Cell Cancers
Monoclon. Antib. Immunodiagn. Immunother., 41(6), 320–327, https://doi.org/10.1089/mab.2021.0049, 2022 (PDF)

25. Nanamiya R, Suzuki H, Takei J, Li G, Goto N, Harada H, Saito M, Tanaka T, Asano T, Kaneko MK, Kato Y.
Development of Monoclonal Antibody 281-mG2a-f Against Golden Hamster Podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 41(6), 311–319, https://doi.org/10.1089/mab.2021.0058, 2022 (PDF)

24. Tanaka T, Suzuki H, Isoda Y, Asano T, Nakamura T, Yanaka M, Handa S, Takahashi N, Okuno S, Yoshikawa T, Li G, Nanamiya R, Goto N, Tateyama N, Okada Y, Kobayashi H, Kaneko MK, Kato Y.
Development of a Sensitive Anti-human CCR9 Monoclonal Antibody (C9Mab-11) by N-terminal Peptide Immunization
Monoclon. Antib. Immunodiagn. Immunother., 41(6), 303–310, doi: 10.1089/mab.2022.0027, 2022 (PDF)

23. Yamamoto Y, Inoue T, Inoue M, Murae M, Fukasawa M, Kaneko MK, Kato Y, Noguchi K.
SARS-Cov-2 Spike Protein Mutation at Cysteine-488 Impairs Its Golgi Localization And Intracellular S1/S2 Processing
Int. J. Mol. Sci., 23(24), 15834; https://doi.org/10.3390/ijms232415834, 2022 (PDF)

22. Machitani M, Takei J, Kaneko MK, Ueki S, Ohashi H, Watashi K, Kato Y, Masutomi K.
Development of novel monoclonal antibodies against nsp12 of SARS-CoV-2
Virol J., 19(1):213. doi: 10.1186/s12985-022-01948-2, 2022 (PDF)

21. Tateyama N, Asano T, Suzuki H, Li G, Yoshikawa T, Tanaka T, Kaneko MK, Kato Y.
Epitope Mapping of Anti-mouse CCR3 Monoclonal Antibodies using Flow Cytometry
antibodies, 11(4), 75; https://doi.org/10.3390/antib11040075, 2022 (PDF)

20. Asano T, Tanaka T, Suzuki H, Li G, Ohishi T, Kawada M, Yoshikawa T, Kaneko MK, Kato Y.
A Defucosylated Anti-EpCAM Monoclonal Antibody (Ep-Mab-37-mG2a-f) Exerts Antitumor Activity in Xenograft Model
antibodies, 11(4), 74; https://doi.org/10.3390/antib11040074, 2022 (PDF)

19. Tateyama N, Suzuki H, Ohishi T, Asano T, Tanaka T, Mizuno T, Yoshikawa T, Kawada M, Kaneko MK, Kato Y.
Antitumor Activity of an anti-EGFR/HER2 Bispecific Antibody in a Mouse Xenograft Model of Canine Osteosarcoma
pharmaceutics,14(11), 2494; https://doi.org/10.3390/pharmaceutics14112494, 2022 (PDF)

18. Isoda Y, Tanaka T, Suzuki H, Asano T, Nakamura T, Yanaka M, Handa S, Komatsu Y, Okuno S, Takahashi N, Okada Y, Kobayashi H, Li G, Nanamiya R, Goto N, Tateyama N, Yoshikawa T, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-mouse CXCR6 Monoclonal Antibody (Cx6Mab-1) using the 2×Alanine scanning method
Monoclon. Antib. Immunodiagn. Immunother.,41(5),275–278, DOI: 10.1089/mab.2022.0019, 2022 (PDF)

17. Tanaka T, Suzuki H, Li G, Nanamiya R, Isoda Y, Okada Y, Kobayashi H, Yoshikawa T, Kaneko MK, Kato Y.
Epitope Mapping of the Anti-Human CCR2 Monoclonal Antibody (K036C2)
Monoclon. Antib. Immunodiagn. Immunother.,41(5),285–289, DOI: 10.1089/mab.2022.0018, 2022 (PDF)

16. Saito M, Suzuki H, Asano T, Tanaka T, Yoshikawa T, Kaneko MK, Kato Y.
KLMab-1: An Anti-Human KLRG1 Monoclonal Antibody for Immunocytochemistry
Monoclon. Antib. Immunodiagn. Immunother.,41(5),279–284, https://doi.org/10.1089/mab.2022.0016, 2022 (PDF)

15. Sajiki Y, Konnai S, Watari K, Okagawa T, Tanaka A, Kawaji S, Nagata R, Maekawa N, Suzuki Y, Kato Y, Murata S, Mori Y, Ohashi K.
Prostaglandin E2-Induced Immune Suppression via Cytotoxic T-Lymphocyte Antigen 4 in Paratuberculosis
Infect Immun ;90(10):e0021022, doi: 10.1128/iai.00210-22. 2022　(PDF)

14. Ishikawa A, Waseda M, Ishii T, Kaneko MK, Kato Y, Kaneko S.
Improved anti-solid tumor response by humanized anti-podoplanin chimeric antigen receptor transduced human cytotoxic T cells in animal model
Genes Cells,27(9), 549-558, https://doi.org/10.1111/gtc.12972, 2022 (PDF)

13. Tanaka T, Li G, Saito M, Suzuki H, Asano T, Kaneko MK, Kato Y.
Development of an Anti-human CCR2 Monoclonal Antibody (C2Mab-9) by N-terminal Peptide Immunization
Monoclon. Antib. Immunodiagn. Immunother., 41(4), 188–193, https://doi.org/10.1089/mab.2022.0001, 2022 (PDF)

12. Kudo Y, Suzuki H, Kaneko MK, Kato Y.
Development of a Monoclonal Antibody PMab-295 Against Elephant Podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 41(4), 194–201, https://doi.org/10.1089/mab.2022.0007, 2022 (PDF)

11. Asano T, Suzuki H, Tanaka T, Kaneko MK, Kato Y.
Identification of the Binding Epitope of an Anti-Mouse CCR4 Monoclonal Antibody, C4Mab-1
Monoclon. Antib. Immunodiagn. Immunother., 41(4), 214–220, https://doi.org/10.1089/mab.2022.0015, 2022 (PDF)

10. Okada Y, Suzuki H, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-Elephant Podoplanin Monoclonal Antibody (PMab-295) using Enzyme-Linked Immunosorbent Assay
Monoclon. Antib. Immunodiagn. Immunother., 41(4), 221–227, https://doi.org/10.1089/mab.2022.0017, 2022 (PDF)

9. Imaizumi Y, Takanuki K, Miyake T, Takemoto M, Hirata K, Hirose M, Oi R, Kobayashi T, Miyoshi K, Aruga R, Yokoyama T, Katagiri S, Matsuura H, Iwasaki K, Kato T, Kaneko MK, Kato Y, Tajiri M, Akashi S, Nureki O, Hizukuri Y, Akiyama Y, Nogi T.
Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP
Sci Adv.,8(34):eabp9011, DOI: 10.1126/sciadv.abp9011, 2022 (PDF)

8. Suzuki H, Ohishi T, Asano T, Tanaka T, Saito M, Mizuno T, Yoshikawa T, Kawada M, Kaneko MK, Kato Y.
Defucosylated mouse-dog chimeric anti-HER2 monoclonal antibody exerts antitumor activities in mouse xenograft models of canine tumors
Oncol. Rep.,,48(3), 154, https://doi.org/10.3892/or.2022.8366, 2022 (PDF)

7. Saito M, Suzuki H, Kaneko MK, Kato Y.
TgMab-2: An Anti-Human TIGIT Monoclonal Antibody for Immunocytochemistry
Monoclon. Antib. Immunodiagn. Immunother., 41(3), 157–162, https://doi.org/10.1089/mab.2022.0013, 2022 (PDF)

6. Tanaka T, Li G, Asano T, Kaneko MK, Suzuki H, Kato Y.
Epitope Mapping of the Anti-Human CCR2 Monoclonal Antibody C2Mab-9
Monoclon. Antib. Immunodiagn. Immunother., 41(3), 150–156, https://doi.org/10.1089/mab.2022.0012, 2022 (PDF)

5. Goto N, Suzuki H, Tanaka T, Asano T, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-Chinese/golden Hamster Podoplanin Monoclonal Antibody
Monoclon. Antib. Immunodiagn. Immunother., 41(3), 163–169, https://doi.org/10.1089/mab.2022.0014, 2022 (PDF)

4. Kitamura K, Suzuki H, Kaneko MK, Kato Y.
Cx6Mab-1: a Novel Anti-mouse CXCR6 Monoclonal Antibody established by N-terminal Peptide Immunization
Monoclon. Antib. Immunodiagn. Immunother., 41(3), 133–141, https://doi.org/10.1089/mab.2022.0010, 2022 (PDF)

3. Alam M, Shima H, Matsuo Y, Nguyen CL, Matsumoto M, Ishii Y, Sato N, Sugiyama T, Nobuta R, Hashimoto S, Liu L, Kaneko MK, Kato Y, Inada T, Igarashi K.
mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine
J Biol Chem, 298(7),102084, doi: 10.1016/j.jbc.2022.102084., 2022 (PDF)

2. Li G, Suzuki H, Asano T, Tanaka T, Suzuki H, Kaneko MK, Kato Y.
Development of A Novel Anti-EpCAM Monoclonal Antibody for Various Applications
Antibodies, 11(2), 41; https://doi.org/10.3390/antib11020041, 2022 (PDF) (Preprint)

1. Goto N, Suzuki H, Tanaka T, Asano T, Kaneko MK, Kato Y.
Development of a novel anti-CD44 monoclonal antibody for multiple applications against esophageal squamous cell carcinomas
Int. J. Mol. Sci., 23(10), 5535; https://doi.org/10.3390/ijms23105535, 2022 (PDF) (Preprint)



・・・・・・・・・・・・
以下、BINDS　Phase Iの業績
・・・・・・・・・・・・

2022

178. Fujii K, Morita S, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Yamaguchi K, Abe J, Yamazaki T, Imai T, Sugamura K, Yasuda J, Satoh K, Sato I, Saito-Koyama R, Fujishima F, Sasano H, Kato Y, Matsuura K, Asada Y, Tamai K.
Establishment of a monoclonal antibody against glycosylated CD271 specific for cancer cells in immunohistochemistry
Cancer Sci., 113(8),2878-2887, doi: 10.1111/cas.15340., 2022 (PDF)

177. Chalise L, Kato A, Ohno M, Maeda S, Yamamichi A, Kuramitsu S, Shiina S, Takahashi H, Ozone S, Yamaguchi J, Kato Y, Rockenbach Y, Natsume A, Todo T.
Efficacy of cancer-specific anti-podoplanin CAR-T cells and oncolytic herpes virus G47delta combination therapy against glioblastoma
Mol Ther Oncolytics, 26, 265-274, https://doi.org/10.1016/j.omto.2022.07.006, 2022 (PDF)

176. Saito M, Harigae Y, Li G, Asano T, Tanaka T, Suzuki H, Kaneko MK, Kato Y.
C3Mab-2: An Anti-Mouse CCR3 Monoclonal Antibody for Immunocytochemistry
Monoclon. Antib. Immunodiagn. Immunother.,41(1), 45–49, DOI: 10.1089/mab.2021.0050, 2022 (PDF)

175. Li G, Suzuki H, Takei J, Saito M, Goto N, Uchida K, Nakagawa T, Harada H, Tanaka T, Asano T, Kaneko MK, Kato Y.
Immunohistochemical Analysis using Monoclonal Antibody PMab-269 against Steller Sea Lion Podoplanin
Monoclon. Antib. Immunodiagn. Immunother.,41(1), 39–44, DOI: 10.1089/mab.2021.0055, 2022 (PDF)

174. Kawabata H, Suzuki H, Takei J, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-CD10 Monoclonal Antibody (MME/1870) using Enzyme-Linked Immunosorbent Assay
Monoclon. Antib. Immunodiagn. Immunother.,41(1), 15–19, DOI: 10.1089/mab.2021.0046, 2022 (PDF)

173. Asano T, Suzuki H, Kaneko MK, Kato Y.
Epitope Mapping of Rituximab using HisMAP Method
Monoclon. Antib. Immunodiagn. Immunother.,41(1), 8–14, DOI: 10.1089/mab.2021.0044, 2022 (PDF)

172. Nanamiya R, Takei J, Ohishi T, Asano T, Tanaka T, Sano M, Nakamura T, Yanaka M, Handa S, Tateyama N, Harigae Y, Saito M, Suzuki H, Kawada M, Kaneko MK, Kato Y.
Defucosylated Anti-EGFR Monoclonal Antibody (134-mG2a-f) Exerts Antitumor Activities in Mouse Xenograft Models of Canine Osteosarcoma
Monoclon. Antib. Immunodiagn. Immunother., 41(1), 1–7, DOI: 10.1089/mab.2021.0036, 2022 (PDF)

171. Tanaka T, Ohishi T, Saito M, Kawada M, Kaneko MK, Kato Y.
TrMab-6 Exerts Antitumor Activity in Mouse Xenograft Models of Breast Cancers
Monoclon. Antib. Immunodiagn. Immunother.,41(1), 32–38, DOI: 10.1089/mab.2021.0056, 2022 (PDF)

170. Suzuki H, Asano T, Tanaka T, Kaneko MK, Kato Y.
Epitope Mapping of the Anti-CD20 Monoclonal Antibodies (C20Mab-11 and 2H7) using HisMAP method
Monoclon. Antib. Immunodiagn. Immunother.,41(1), 20–26, DOI: 10.1089/mab.2021.0051, 2022 (PDF)

169. Suzuki H, Kaneko MK, Kato Y.
Roles of Podoplanin in Malignant Progression of Tumor
Cells, 11(3), 575; https://doi.org/10.3390/cells11030575, 2022 (PDF)
(Preprint, doi: 10.20944/preprints202201.0280.v1, 2022)

168. Nishikawa T, Watanabe R, Kitano Y, Yamamichi A, Motomura K, Ohka F, Aoki K, Hirano M, Kato A, Yamaguchi J, Maeda S, Kibe Y, Saito R, Wakabayashi T, Kato Y, Sato S, Ogino T, Natsume A, Ito I.
Reliability of IDH1-R132H and ATRX and/or p53 immunohistochemistry for molecular subclassification of Grade 2/3 gliomas
Brain Tumor Pathol., 39, pages 14–24, doi: 10.1007/s10014-021-00418-x, 2022 (PDF)

167. Watari K, Konnai S, Maekawa N, Okagawa T, Sajiki Y, Kato Y, Suzuki Y, Murata S, Ohashi K.
Enhancement of interleukin-2 production by bovine peripheral blood mononuclear cells treated with the combination of anti-programmed death-ligand 1 and cytotoxic T lymphocyte antigen 4 chimeric monoclonal antibodies
J Vet Med Sci, 84(1), 6-15, doi: 10.1292/jvms.21-0552, 2022 (PDF)

2021

166. Takei J, Suzuki H, Asano T, Li G, Saito M, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-CD20 Monoclonal Antibody (C20Mab-60) using Enzyme-Linked Immunosorbent Assay
Monoclon. Antib. Immunodiagn. Immunother.,40(6), 250–254, https://doi.org/10.1089/mab.2021.0042, 2021 (PDF)

165. Takei J, Asano T, Li G, Saito M, Suzuki H, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-Human CCR9 Monoclonal Antibody (C9Mab-1) using Enzyme-Linked Immunosorbent Assay
Monoclon. Antib. Immunodiagn. Immunother.,40(6), 239–242, https://doi.org/10.1089/mab.2021.0037, 2021 (PDF)

164. Nakano T, Tanaka T, Sakane F, Kaneko MK, Kato Y, Goto K.
Immunocytochemical Analysis of DGKh in Cultured Cells using a Monoclonal Antibody DhMab-4
Monoclon. Antib. Immunodiagn. Immunother.,40(6), 261–265, https://doi.org/10.1089/mab.2021.0034, 2021 (PDF)

163. Asano T, Takei J, Suzuki H, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-HER2 Monoclonal Antibody (H2Mab-181) using Enzyme-Linked Immunosorbent Assay
Monoclon. Antib. Immunodiagn. Immunother.,40(6), 255–260, DOI: 10.1089/mab.2021.0029, 2021 (PDF)

162. Asano T, Takei J, Furusawa Y, Saito M, Suzuki H, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-CD20 Monoclonal Antibody (C20Mab-60) using the HisMAP Method
Monoclon. Antib. Immunodiagn. Immunother.,40(6), 243–249, DOI: 10.1089/mab.2021.0035, 2021 (PDF)

161. Li G, Ohishi T, Kaneko MK, Takei J, Mizuno T, Kawada M, Saito M, Suzuki H, Kato Y.
Defucosylated Mouse–Dog Chimeric Anti-EGFR Antibody Exerts Antitumor Activities in Mouse Xenograft Models of Canine Tumors
Cells, 10(12), 3599; https://doi.org/10.3390/cells10123599, 2021 (PDF)

160. Kamoto S, Shinada M, Kato D, Tsuboi M, Yoshimoto S, Yoshitake R, Eto S, Ikeda N, Takahashi Y, Hashimoto Y, Chambers J, Uchida K, Yamada S, Kaneko MK, Nishimura R, Kato Y, Nakagawa T.
Expression of podoplanin in various types of feline tumor tissues.
J Vet Med Sci, 83(11),1795-1799, https://doi.org/10.1292/jvms.20-0608, 2021 (PDF)

159. Ganbaatar O, Konnai S, Okagawa T, Nojima Y, Maekawa N, Ichikawa Y, Kobayashi A, Shibahara T, Yanagawa Y, Higuchi H, Kato Y, Suzuki Y, Murata S, Ohashi K.
Programmed death-ligand 1 expression in swine chronic infections and enhancement of interleukin-2 production via programmed death-1/programmed death-ligand 1 blockade
Immun Inflamm Dis., 9(4), 1573-1583, doi: 10.1002/iid3.510, 2021 (PDF)

158. Takei J, Asano T, Suzuki H, Kaneko MK, Kato Y.
Epitope mapping of the anti-CD44 monoclonal antibody (C44Mab-46) using alanine-scanning mutagenesis and surface plasmon resonance
Monoclon. Antib. Immunodiagn. Immunother., DOI: 10.1089/mab.2021.0028, 2021 (PDF)

157. Asano T, Suzuki H, Kaneko MK, Kato Y.
Epitope Mapping of a Cancer-specific Anti-podocalyxin Monoclonal Antibody (PcMab-60) using Enzyme-linked Immunosorbent Assay and Surface Plasmon Resonance
Monoclon. Antib. Immunodiagn. Immunother., DOI: 10.1089/mab.2021.0030, 2021 (PDF)

156. Sudo H, Tsuji AB, Sugyo A, Kaneko MK, Kato Y, Nagatsu K, Suzuki H, Higashi T.
Preclinical evaluation of podoplanin-targeted al-pha-radioimmunotherapy with the novel antibody NZ-16 for malignant mesothelioma
Cells, 10(10), 2503; https://doi.org/10.3390/cells10102503, 2021 (PDF)

155. Tateyama N, Asano T, Ohishi T, Takei J, Hosono H, Nanamiya R, Tanaka T, Sano M, Saito M, Kawada M, Kaneko MK, Kato Y.
An Anti‐HER2 Monoclonal Antibody H2Mab‐41 Exerts Antitumor Activities in Mouse Xenograft Model using Dog HER2‐overexpressed Cells
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 184–190, DOI: 10.1089/mab.2021.0025, 2021　(PDF)

154. Tateyama N, Nanamiya R, Ohishi T, Takei J, Nakamura T, Yanaka M, Hosono H, Saito M, Asano T, Tanaka T, Sano M, Kawada M, Kaneko MK, Kato Y.
Defucosylated Anti-EGFR Monoclonal Antibody 134-mG2a-f Exerts Antitumor Activities in Mouse Xenograft Models of Dog EGFR-overexpressed Cells
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 177–183, DOI: 10.1089/mab.2021.0022, 2021　(PDF)

153. Asano T, Kaneko MK, Kato Y.
Development of a novel epitope mapping system: RIEDL insertion for epitope mapping method
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 162–167, DOI: 10.1089/mab.2021.0023, 2021　(PDF)

152. Nanamiya R, Sano M, Asano T, Yanaka M, Nakamura T, Saito M, Tanaka T, Hosono H, Tateyama N, Kaneko MK, Kato Y.
Epitope Mapping of an Anti-Human EGFR Monoclonal Antibody (EMab-51) using the REMAP Method
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 149–155, DOI: 10.1089/mab.2021.0010, 2021　(PDF)

151. Junko Takei, Teizo Asano, Tomohiro Tanaka, Masato Sano, Hideki Hosono, Ren Nanamiya, Nami Tateyama, Masaki Saito, Hiroyoshi Suzuki, Hiroyuki Harada, Mika K. Kaneko, Yukinari Kato.
Development of a Novel Anti-HER2 Monoclonal Antibody H2Mab-181 for Gastric Cancer
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 168–176, DOI: 10.1089/mab.2021.0021, 2021　(PDF)

150. Asano T, Kaneko MK, Takei J, Tateyama N, Kato Y.
Epitope Mapping of the Anti-CD44 Monoclonal Antibody (C44Mab-46) Using the REMAP Method
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 156–161, DOI: 10.1089/mab.2021.0012, 2021 (PDF)

149. Sano M, Kaneko MK, Asano T, Kato Y.
Epitope Mapping of an Anti-human EGFR Monoclonal Antibody (EMab-134) using the REMAP Method
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 191–195, DOI: 10.1089/mab.2021.0014, 2021　(PDF)

148. Tanaka T, Asano T, Sano M, Takei J, Hosono H, Nanamiya R, Tateyama N, Kaneko MK, Kato Y.
Epitope Mapping of the Anti-California Sea Lion Podoplanin Monoclonal Antibody PMab-269 using Alanine-scanning Mutagenesis and ELISA
Monoclon. Antib. Immunodiagn. Immunother., 40(4), 196–200, DOI: 10.1089/mab.2021.0017, 2021 (PDF)

147. Asano T, Ohishi T, Takei J, Nakamura T, Nanamiya R, Hosono H, Tanaka T, Sano M, Harada H, Kawada M, Kaneko MK, Kato Y.
Anti-HER3 monoclonal antibody exerts antitumor activity in a mouse model of colorectal adenocarcinoma
Oncol. Rep., 46(2): 173, https://doi.org/10.3892/or.2021.8124, 2021 (PDF)

146. Nanamiya R, Takei J, Asano T, Sano M, Tanaka T, Hosono H, Harada H, Sakai Y, Mizuno T, Suzuki H, Kaneko MK, Kato Y.
Ferret Podoplanin is Detected by PMab-241 in Immunohistochemistry
Monoclon. Antib. Immunodiagn. Immunother.,40(3),134–140, DOI: 10.1089/mab.2021.0016, 2021 (PDF)

145. Nanamiya R, Takei J, Asano T, Tanaka T, Sano M, Nakamura T, Yanaka M, Hosono H, Kaneko MK, Kato Y.
Development of Anti-Human CC Chemokine Receptor 9 Monoclonal Antibodies for Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother.,40(3), 101–106, DOI: 10.1089/mab.2021.0007, 2021 (PDF)

144. Hosono H, Asano T, Takei J, Sano M, Tanaka T, Kaneko MK, Kato Y
Development of an Anti-Elephant Podoplanin Monoclonal Antibody PMab-265 for Flow cytometry
Monoclon. Antib. Immunodiagn. Immunother., 40(3), 141–145, DOI: 10.1089/mab.2021.0015, 2021 (PDF)

143. Tanaka T, Asano T, Sano M, Takei J, Hosono H, Nanamiya R, Nakamura T, Yanaka M, Harada H, Fukui M, Suzuki H, Uchida K, Nakagawa T, Kato Y, Kaneko MK.
Development of Monoclonal Antibody PMab-269 Against California Sea Lion Podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 40(3), 124–133, DOI: 10.1089/mab.2021.0011, 2021 (PDF)

142. Asano A, Nanamiya R, Takei J, Nakamura T, Yanaka M, Hosono H, Tanaka T, Sano M, Kaneko MK, Kato Y.
Development of Anti-Mouse CC Chemokine Receptor 3 Monoclonal Antibodies for Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother., 40(3), 107–112, DOI: 10.1089/mab.2021.0009, 2021 (PDF)

141. Nosaki S, Kaneko MK, Tsuruta F, Yoshida H, Kato Y, Miura K.
Prevention of necrosis caused by transient expression in Nicotiana benthamiana by application of ascorbic acid
Plant Physiol., 186(2), 832–835, https://doi.org/10.1093/plphys/kiab102, 2021 (PDF)

140. Kanayama M, Oyama R, Mori M, Taira A, Shinohara S, Kuwata T, Takenaka M, Yoneda K, Kuroda K, Ohnaga T, Kato Y, Tanaka F.
Novel circulating tumor cell‑detection chip combining conventional podoplanin and EGFR antibodies for all histological malignant pleural mesothelioma
Oncol. Lett., 22(1), 522 https://doi.org/10.3892/ol.2021.12783, 22(1), 522, 2021 (PDF)

139. Tanaka T, Ohishi T, Asano T, Takei J, Nanamiya R, Hosono H, Sano M, Harada H, Kawada M, Kaneko MK, Kato Y.
An anti-TROP2 monoclonal antibody TrMab-6 exerts antitumor activity in breast cancer mouse xenograft models
Oncology Reports, 46(1), 132, https://doi.org/10.3892/or.2021.8083, 2021 (PDF)

138. Tamura-Sakaguchi R, Aruga R, Hirose M, Ekimoto T, Miyake T, Hizukuri Y, Oi R, Kaneko M, Kato Y, Akiyama Y, Ikeguchi M, Iwasaki K, Nogi T.
Moving toward generalizable NZ-1 labeling for 3D structure determination with optimized epitope tag insertion
Acta Crystallogr D Struct Biol., 77(Pt 5):645-662, doi: 10.1107/S2059798321002527, 2021　(PDF)

137. Tanaka T, Nanamiya R, Takei J, Nakamura T, Yanaka M, Hosono H, Sano M, Asano T, Kaneko MK, Kato Y*.
(*corresponding author)
Development of Anti-Mouse CC chemokine receptor 8 Monoclonal Antibodies for Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother.,40(2), 65–70, DOI: 10.1089/mab.2021.0005, 2021 (PDF)

136. Asano T, Nanamiya R, Tanaka T, Kaneko MK, Kato Y*.
(*corresponding author)
Development of anti-human killer cell lectin-like receptor subfamily G member 1 monoclonal antibodies for flow cytometry
Monoclon. Antib. Immunodiagn. Immunother.,40(2), 76–80, DOI: 10.1089/mab.2021.0008, 2021 (PDF)

135. Takei J, Asano T, Nanamiya R, Nakamura T, Yanaka M, Hosono H, Tanaka T, Sano M, Kaneko MK, Harada H, Kato Y*.
(*corresponding author)
Development of Anti-Human T-Cell Immunoreceptor with Ig and ITIM Domains (TIGIT) Monoclonal Antibodies for Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother.,40(2),71–75, DOI: 10.1089/mab.2021.0006, 2021 (PDF)

134. Sajiki Y, Konnai S, Nagata R, Kawaji S, Nakamura H, Fujisawa S, Okagawa T, Maekawa N, Kato Y, Suzuki Y, Murata S, Mori Y, Ohashi K.
The enhancement of Th1 immune response by anti-PD-L1 antibody in cattle infected with Mycobacterium avium subsp. paratuberculosis
J Vet Med Sci.,83(2),162-166, https://doi.org/10.1292/jvms.20-0590, 2021 (PDF)

133. Maekawa N, Konnai S, Nishimura M, Kagawa Y, Takagi S, Hosoya K, Ohta H, Kim S, Okagawa T, Izumi Y, Deguchi T, Kato Y, Yamamoto S, Yamamoto K, Toda M, Nakajima C, Suzuki Y, Murata S, Ohashi K.
PD-L1 immunohistochemistry for canine cancers and clinical benefit of anti-PD-L1 antibody in dogs with pulmonary metastatic oral malignant melanoma
NPJ Precis Oncol.,5(1):10;doi: 10.1038/s41698-021-00147-6, 2021　(PDF)

132. Sayama Y, Kaneko MK, Takei J, Hosono H, Sano M, Asano T, Kato Y.
Establishment of a novel anti-TROP2 monoclonal antibody TrMab-29 for immunohistochemical analysis
Biochem Biophys Rep.,25, 100902, https://doi.org/10.1016/j.bbrep.2020.100902, 2021 (PDF)

131. Sayama Y, Kaneko MK, Kato Y.
Development and characterization of TrMab-6, a novel anti-TROP2 monoclonal antibody for antigen detection in breast cancer
Mol Med Rep., 23(2), article number-92, https://doi.org/10.3892/mmr.2020.11731, 2021 (PDF)

130. Sajiki Y, Konnai S, Okagawa T, Maekawa N, Nakamura H, Kato Y, Suzuki Y, Murata S, Ohashi K
A TLR7 agonist activates bovine Th1 response and exerts antiviral activity against bovine leukemia virus
Dev Comp Immunol., 114, 103847, https://doi.org/10.1016/j.dci.2020.103847, 2021 (PDF)

2020

129. Yamato Sajiki, Satoru Konnai, Zimeng Cai, Kensuke Takada, Tomohiro Okagawa, Naoya Maekawa, Sotaro Fujisawa, Yukinari Kato, Yasuhiko Suzuki, Shiro Murata, Kazuhiko Ohashi
Enhanced immunotherapeutic efficacy of anti-PD-L1 antibody by combination with EP4 antagonist
ImmunoHorizons, 4 (12) 837-850; DOI: https://doi.org/10.4049/immunohorizons.2000089, 2020 (PDF)

128. Kamoto S, Shinada M, Kato D, Yoshimoto S, Ikeda N, Tsuboi M, Yoshitake R, Eto S, Hashimoto Y, Takahashi Y, Chambers J, Uchida K, Kaneko MK, Fujita N, Nishimura R, Kato Y, Nakagawa T.
Phase I/II Clinical Trial of the Anti-Podoplanin Monoclonal Antibody Therapy in Dogs with Malignant Melanoma
Cells, 9(11), 2529; https://doi.org/10.3390/cells9112529, 2020 (PDF)

127. Ganbaatar O, Konnai S, Okagawa T, Nojima Y, Maekawa N, Minato E, Kobayashi A, Ando R, Sasaki N, Miyakoshi D, Ichii O, Kato Y, Suzuki Y, Murata S, Ohashi K.
Characterization of anti-PD-L1 blocking antibody in horse and PD-L1 expression in equine malignant melanoma
PLoS One, 15(11):e0234218., doi: 10.1371/journal.pone.0234218, 2020 (PDF)

126. Kaneko MK, Ohishi T, Takei J, Sano M, Nakamura T, Hosono H, Yanaka M, Asano T, Sayama Y, Harada H, Kawada M, Kato Y.*
(*corresponding author)
The Anti-EpCAM monoclonal antibody (EpMab-16) exerts anti-tumor activity against oral squamous cell carcinomas
Oncol Rep., 44(6), 2517-2526, https://doi.org/10.3892/or.2020.7808, 2020 (PDF)

125. Wakasa A, Kaneko MK, Kato Y, Takagi J, Arimori T.
Site-specific epitope insertion into recombinant proteins using the MAP tag system
J Biochem. 168(4), 375–384, mvaa054. doi: 10.1093/jb/mvaa054, 2020 (PDF)

124. Hosono H, Ohishi T, Takei J, Asano T, Sayama Y, Kawada M, Kaneko MK, Kato Y.*
(*corresponding author)
The anti-EpCAM monoclonal antibody EpMab-16 exerts antitumor activity in a mouse model of colorectal adenocarcinoma
Oncol Lett., 20: 383, https://www.spandidos-publications.com/10.3892/ol.2020.12246, 2020 (PDF)

123. Kaneko MK, Ohishi T, Nakamura T, Inoue H, Takei J, Sano M, Asano T, Sayama Y, Hosono H, Suzuki H, Kawada M, Kato Y.*
(*corresponding author)
Development of Core-fucose Deficient Humanized and Chimeric Anti-Human Podoplanin Antibodies
Monoclon. Antib. Immunodiagn. Immunother., 39(5), 167–174, https://doi.org/10.1089/mab.2020.0019, 2020 (PDF)

122. Ogasawara S, Suzuki K, Naruchi K, Nakamura S, Shimabukuro J, Tsukahara N, Kaneko MK, Kato Y, Murata T.
Crystal structure of an anti-podoplanin antibody bound to a disialylated O-linked glycopeptide
Biochem Biophys Res Commun., 533(1), 57-63, https://doi.org/10.1016/j.bbrc.2020.08.103, 2020 (PDF)

121. Kaneko MK, Ohishi T, Kawada M, Kato Y.
A cancer-specific anti-podocalyxin monoclonal antibody (60-mG2a-f) exerts antitumor effects in mouse xenograft models of pancreatic carcinoma
Biochem Biophys Rep., 24, 100826, https://doi.org/10.1016/j.bbrep.2020.100826, 2020 (PDF)

120. Takei J, Kaneko MK, Ohishi T, Hosono H, Nakamura T, Yanaka M, Sano M, Asano T, Sayama Y, Kawada M, Harada H, Kato Y.*
(*corresponding author)
A defucosylated anti-CD44 monoclonal antibody 5-mG2a-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
Oncol Rep., 44: 1949-1960, https://doi.org/10.3892/or.2020.7735, 2020 (PDF)

119. Miura K, Yoshida H, Nosaki S, Kaneko MK, Kato Y.
RAP tag and PMab-2 antibody: a tagging system for detecting and purifying proteins in plant cells
Front. Plant Sci.,11, 510444, doi: 10.3389/fpls.2020.510444, 2020 (PDF)

118. Sano M, Asano T, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope mapping of an anti-diacylglycerol kinase delta monoclonal antibody DdMab-1
Biochem Biophys Rep., 24, 100808, https://doi.org/10.1016/j.bbrep.2020.100808, 2020 (PDF)

117. Takei J, Ohishi T, Kaneko MK, Harada H, Kawada M, Kato Y.*
(*corresponding author)
A defucosylated anti-PD-L1 monoclonal antibody 13-mG2a-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
Biochem Biophys Rep.,, 24, 100801, https://doi.org/10.1016/j.bbrep.2020.100801, 2020 (PDF)

116. Kaneko MK, Sano M, Takei J, Asano T, Sayama Y, Hosono H, Kobayashi A, Konnai S, Kato Y.*
(*corresponding author)
Development and Characterization of Anti-Sheep Podoplanin Monoclonal Antibodies PMab-253 and PMab-260
Monoclon. Antib. Immunodiagn. Immunother., 39(4):144–155 DOI: 10.1089/mab.2020.0018, 2020 (PDF)

115. Furusawa Y, Kaneko MK, Kato Y*
(*corresponding author)
Establishment of an Anti-CD20 Monoclonal Antibody (C20Mab-60) for Immunohistochemical Analyses
Monoclon. Antib. Immunodiagn. Immunother.,39(4):112–116, DOI: 10.1089/mab.2020.0015, 2020　(PDF)

114. Kato Y*, Ohishi T, Takei J, Nakamura T, Kawada M, Kaneko MK.
(*corresponding author)
An anti-human epidermal growth factor receptor 2 monoclonal antibody (H2Mab-19) exerts antitumor activity in glioblastoma xenograft models
Monoclon. Antib. Immunodiagn. Immunother.,39(4):135–139, https://doi.org/10.1089/mab.2020.0013, 2020 (PDF)

113.Sano M, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope mapping of DhMab-1, an anti-diacylglycerol kinase monoclonal antibody
Monoclon. Antib. Immunodiagn. Immunother.,39(4):140–143, https://doi.org/10.1089/mab.2020.0014, 2020 (PDF)

112. Kato Y*, Ohishi T, Takei J, Nakamura T, Sano M, Asano T, Sayama Y, Hosono H, Kawada M, Kaneko MK.
(*corresponding author)
An anti-human epidermal growth factor receptor 2 monoclonal antibody H2Mab-19 exerts antitumor activity in mouse colon cancer xenografts
Monoclon. Antib. Immunodiagn. Immunother.,39(4):123–128, doi:10.1089/mab.2020.0009, 2020 (PDF)

111. Asano T, Sano M, Takei J, Sayama Y, Kaneko MK, Kato Y*
(*corresponding author)
Epitope mapping of the anti-diacylglycerol kinase monoclonal antibody DhMab-4 for immunohistochemical analysis
Monoclon. Antib. Immunodiagn. Immunother.,39(4):117–122, DOI: 10.1089/mab.2020.0012, 2020 (PDF)

110. Tomokazu Ohishi, Yukinari Kato, Mika K. Kaneko, Shun-ichi Ohba, Hiroyuki Inoue, Akiko Harakawa, Manabu Kawada.
Anti-metastatic activity of an anti-EGFR monoclonal antibody against metastatic colorectal cancer with KRAS p.G13D mutation.
Int. J. Mol. Sci., 21(17), 6037; https://doi.org/10.3390/ijms21176037, 2020 (PDF)

109. Hideki Hosono, Junko Takei, Tomokazu Ohishi, Masato Sano, Teizo Asano, Yusuke Sayama, Takuro Nakamura, Miyuki Yanaka, Manabu Kawada, Hiroyuki Harada, Mika Kato Kaneko, Yukinari Kato*
(*corresponding author)
The anti-EGFR monoclonal antibody 134-mG2a exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
International Journal of Molecular Medicine, 46(4), 1443-1452, 2020, https://doi.org/10.3892/ijmm.2020.4700 (PDF)

108. Asano T, Kaneko MK, Kato Y.*
(*corresponding author)
RIEDL tag: A novel pentapeptide tagging system for transmembrane protein purification
Biochem Biophys Rep., 23, 100780; https://doi.org/10.1016/j.bbrep.2020.100780, 2020　(PDF)

107. Mizuno T, Kato Y, Kaneko MK, Sakai Y, Shiga T, Kato M, Tsukui T, Takemoto H, Tokimasa A, Baba K, Nemoto Y, Sakai O, Igase M.
Generation of a canine anti-canine CD20 antibody for canine lymphoma treatment
Sci. Rep., 10, 11476, https://doi.org/10.1038/s41598-020-68470-9, 2020 (PDF)

106. Kato Y*, Sano M, Asano T, Sayama Y, Kaneko MK.
(*corresponding author)
Thr80 of sheep podoplanin is a critical epitope of the anti-sheep podoplanin monoclonal antibody, PMab-256
Monoclon. Antib. Immunodiagn. Immunother., 39(3):95–100, https://doi.org/10.1089/mab.2020.0010, 2020 (PDF)

105. Kato Y*, Ohishi T, Sano M, Asano T, Sayama Y, Takei J, Kawada M, Kaneko MK.
(*corresponding author)
H2Mab-19 anti-human epidermal growth factor receptor 2 monoclonal antibody therapy exerts antitumor activity in pancreatic cancer xenograft models
Monoclon. Antib. Immunodiagn. Immunother., 39(3):61–65; , https://doi.org/10.1089/mab.2020.0011, 2020 (PDF)

104. Kato Y*, Takei J, Sano M, Asano T, Sayama Y, Uchida K, Nakagawa T, Kaneko MK.
(*corresponding author)
Detection of lion podoplanin using the anti-tiger podoplanin monoclonal antibody PMab-231
Monoclon. Antib. Immunodiagn. Immunother., 39(3):91–94; , https://doi.org/10.1089/mab.2020.0008, 2020 (PDF)

103. Kato Y*, Furusawa Y, Sano M, Takei J, Nakamura T, Yanaka M, Okamoto S, Handa S, Komatsu Y, Asano T, Sayama Y, Kaneko MK.
(*corresponding author)
Development of an Anti-Sheep Podoplanin Monoclonal Antibody PMab-256 for Immunohistochemical Analysis of Lymphatic Endothelial Cells
Monoclon. Antib. Immunodiagn. Immunother., 39(3):82–90; DOI: 10.1089/mab.2020.0005, 2020 (PDF)

102. Sayama Y, Sano M, Asano T, Furusawa Y, Takei J, Nakamura T, Yanaka M, Okamoto S, Handa S, Komatsu Y, Nakamura Y, Yanagawa M, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope mapping of PMab-241, a lymphatic endothelial cell-specific anti-bear podoplanin monoclonal antibody
Monoclon. Antib. Immunodiagn. Immunother., 39(3):77–81; DOI: 10.1089/mab.2020.0004, 2020 (PDF)

101. Mukai C, Choi E, Sams KL, Klampen EZ, Anguish L, Marks BA, Rice EJ, Wang Z, Choate LA, Chou SP, Kato Y, Miller AD, Danko CG, Coonrod SA.
Chromatin run-on sequencing analysis finds that ECM remodeling plays an important role in canine hemangiosarcoma pathogenesis 
BMC Veterinary Research, 16:206, DOI: 10.1186/s12917-020-02395-3, 2020 (PDF)

100. Furusawa Y, Kaneko MK, Kato Y.*
(*corresponding author)
Establishment of C20Mab-11, a novel anti-CD20 monoclonal antibody, for the detection of B cells
Oncol Lett., 20(2), 1961-1967; https://doi.org/10.3892/ol.2020.11753, 2020 (PDF)

99. Goto S, Konnai S, Hirano Y, Kohara J, Okagawa T, Maekawa N, Sajiki Y, Watari K, Minato E, Kobayashi A, Gondaira S, Higuchi H, Koiwa M, Tajima M, Taguchi E, Ishida M, Uemura R, Yamada S, Kaneko M, Kato Y, Yamamoto K, Toda M, Suzuki Y, Murata S, Ohashi K.
Clinical efficacy of the combined treatment of anti-PD-L1 rat-bovine chimeric antibody with a COX-2 inhibitor in calves infected with Mycoplasma bovis
Jpn. J. Vet. Res., 68: 77-90, http://hdl.handle.net/2115/78601, 2020

98. Junko Takei, Mika K. Kaneko, Tomokazu Ohishi, Manabu Kawada, Hiroyuki Harada, Yukinari Kato*
(*corresponding author)
H2Mab-19, an anti-human epidermal growth factor receptor 2 monoclonal antibody exerts antitumor activity in mouse oral cancer xenografts
Exp Ther Med., 20: 846-853, https://doi.org/10.3892/etm.2020.8765, 2020 (PDF)

97. Akiyama G, Saraswathy S, Bogarin T, Pan X, Barron E, Wong TT, Kaneko MK, Kato Y, Hong Y, Huang AS.
Functional, Structural, and Molecular Identification of Lymphatic Outflow from Subconjunctival Blebs  
Exp Eye Res.,196, 108049, https://doi.org/10.1016/j.exer.2020.108049, 2020 (PDF)

96. Shinada M, Kato D, Kamoto S, Yoshimoto S, Tsuboi M, Yoshitake R, Eto S, Ikeda N, Saeki K, Hashimoto Y, Takahashi Y, Chambers J, Uchida K, Kaneko MK, Fujita N, Nishimura R, Kato Y, Nakagawa T.
PDPN is expressed in various types of canine tumors and its silencing induces apoptosis and cell cycle arrest in canine malignant melanoma 
Cells, 9(5):E1136. doi: 10.3390/cells9051136., 2020 (PDF)

95. Nishinaga Y, Sato K, Yasui H, Taki S, Takahashi K, Shimizu M, Endo R, Koike C, Kuramoto N, Nakamura S, Fukui T, Yukawa H, Baba Y, K Kaneko M, Chen-Yoshikawa TF, Kobayashi H, Kato Y, Hasegawa Y.
Targeted Phototherapy for Malignant Pleural Mesothelioma: Near-Infrared Photoimmunotherapy Targeting Podoplanin
Cells,9(4), 1019; https://doi.org/10.3390/cells9041019, 2020 (PDF)

94. Kato Y*, Ito Y, Ohishi T, Kawada M, Nakamura T, Sayama Y, Sano M, Asano T, Yanaka M, Okamoto S, Handa S, Komatsu Y, Takei J, Kaneko MK.
(*corresponding author)
Antibody–drug conjugates using mouse–canine chimeric anti-dog podoplanin antibody exerts antitumor activity in a mouse xenograft model
Monoclon. Antib. Immunodiagn. Immunother., 39(2); 37-44; https://doi.org/10.1089/mab.2020.0001, 2020 (PDF)

93. Yamada S, Kaneko MK, Sayama Y, Asano T, Sano M, Yanaka M, Nakamura T, Okamoto S, Handa S, Komatsu Y, Nakamura Y, Furusawa Y, Takei J, Kato Y.*
(*corresponding author)
Development of novel mouse monoclonal antibodies against human CD19
Monoclon. Antib. Immunodiagn. Immunother., 39(2);45-50; DOI: 10.1089/mab.2020.0003, 2020 (PDF)

92. Kuwata T, Yoneda K, Mori M, Kanayama M, Kuroda K, Kaneko MK, Kato Y, Tanaka F.
Effective detection of circulating tumor cells (CTCs) in malignant pleural mesothelioma (MPM) with the "universal" CTC-chip and an anti-podoplanin antibody NZ-1.2
Cells, 9(4), 888; https://doi.org/10.3390/cells9040888, 2020 (PDF)

91. Yasukawa M, Ando Y, Yamashita T, Matsuda Y, Shoji S, Morioka MS, Kawaji H, Shiozawa K, Machitani M, Abe T, Yamada S, Kaneko MK, Kato Y, Furuta Y, Kondo T, Shirouzu M, Hayashizaki Y, Kaneko S, Masutomi K.
CDK1 dependent phosphorylation of hTERT contributes to cancer progression
Nat Commun.;11(1):1557. doi: 10.1038/s41467-020-15289-7., 2020

90. Sato M, Matsumoto M, Saiki Y, Alam M, Nishizawa H, Rokugo M, Brydun A, Yamada S, Kaneko MK, Funayama R, Ito M, Kato Y, Nakayama K, Unno M, Igarashi K.
BACH1 promotes pancreatic cancer metastasis by repressing epithelial genes and enhancing epithelial-mesenchymal transition
Cancer Res., 80(6):1279-1292.,doi: 10.1158/0008-5472.CAN-18-4099., 2020 (PDF)

89. Takei J, Kaneko MK, Ohishi T, Kawada M, Harada H, Kato Y.*
(*corresponding author)
A novel anti-EGFR monoclonal antibody (EMab-17) exerts antitumor activity against oral squamous cell carcinomas via antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity
Oncol Lett., 19(4), 2809-2816, https://doi.org/10.3892/ol.2020.11384, 2020, (PDF)

88. Goto S, Konnai S, Hirano Y, Kohara J, Okagawa T, Maekawa N, Sajiki Y, Watari K, Minato E, Kobayashi A, Gondaira S, Higuchi H, Koiwa M, Tajima M, Taguchi E, Uemura R, Yamada S, Kaneko M, Kato Y, Yamamoto K, Toda M, Suzuki Y, Murata S, Ohashi K.
Upregulation of PD-L1 expression by prostaglandin E2 and the enhancement of IFN-γ by anti-PD-L1 antibody combined with a COX-2 inhibitor in Mycoplasma bovis infection
Front. Vet. Sci., 7:12. doi: 10.3389/fvets.2020.00012, 2020　(PDF)

87. Sayama Y, Sano M, Kaneko MK, Kato Y*
(*corresponding author)
Epitope analysis of an anti-whale podoplanin monoclonal antibody, PMab-237, using flow cytometry
Monoclon. Antib. Immunodiagn. Immunother., 39(1):17-22, https://doi.org/10.1089/mab.2019.0045, 2020, (PDF)

86.Sano M, Kaneko MK, Suzuki H, Kato Y.*
(*corresponding author)
Establishment and Epitope Mapping of Anti-Diacylglycerol Kinase Alpha Monoclonal Antibody DaMab-8 for immunohistochemical analyses
Monoclon. Antib. Immunodiagn. Immunother., 39(1):1-5, doi: 10.1089/mab.2019.0004.(PDF)



2019

85. Sayama Y, Sano M, Furusawa Y, Kaneko MK, Kato Y*
(*corresponding author)
Epitope Mapping of PMab-225 an Anti-Alpaca Podoplanin Monoclonal Antibody using Flow Cytometry
Monoclon. Antib. Immunodiagn. Immunother., 38(6):255–260, DOI: 10.1089/mab.2019.0033, 2019 (PDF)

84. Takei J, Yamada S, Konnai S, Ishinazaka T, Shimozuru M, Kaneko MK, Kato Y.*
(*corresponding author)
PMab-241 Specifically Detects Bear Podoplanin of Lymphatic endothelial cells in the Lung of Brown Bear
Monoclon. Antib. Immunodiagn. Immunother., 38(6):282–284, https://doi.org/10.1089/mab.2019.0038, 2019 (PDF)

83. Kaneko MK, Sayama Y, Sano M, Kato Y.*
(*corresponding author)
The Epitope of PMab-210 is Located in Platelet Aggregation-Stimulating Domain-3 of Pig Podoplanin
Monoclon. Antib. Immunodiagn. Immunother.,38(6):271–276, https://doi.org/10.1089/mab.2019.0037, 2019 (PDF)

82. Kato Y*, Sayama Y, Sano M, Kaneko MK.
(*corresponding author)
Epitope Analysis of an Anti-Horse Podoplanin Monoclonal Antibody PMab-219
Monoclon. Antib. Immunodiagn. Immunother.,38(6):266–270 https://doi.org/10.1089/mab.2019.0034, 2019 (PDF)

81. Sano M, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope Mapping of Monoclonal Antibody PMab-233 Against Tasmanian Devil Podoplanin
Monoclon. Antib. Immunodiagn. Immunother.,38(6): 261–265, DOI: 10.1089/mab.2019.0032, 2019 (PDF)

80. Sakamoto S, Inoue H, Kaneko MK, Ogasawara S, Kajikawa M, Urano S, Ohba SI, Kato Y, Kawada M.
Generation and evaluation of a chimeric antibody against coxsackievirus and adenovirus receptor for cancer therapy
Cancer Sci., 110(11):3595-3602, https://doi.org/10.1111/cas.14196, 2019, (PDF)

79. Kato Y*, Takei J, Furusawa Y, Sayama Y, Sano M, Konnai S, Kobayashi A, Harada H, Takahashi M, Suzuki H, Yamada S, Kaneko MK.
(*corresponding author)
Epitope mapping of anti-bear podoplanin monoclonal antibody PMab-247
Monoclon. Antib. Immunodiagn. Immunother., 38(5): 230–233, https://doi.org/10.1089/mab.2019.0025, 2019 (PDF)

78. Yamada S, Itai S, Furusawa Y, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope mapping of anti-pig podoplanin monoclonal antibody PMab-213
Monoclon. Antib. Immunodiagn. Immunother., 38(5): 224–229, https://doi.org/10.1089/mab.2019.0023, 2019　(PDF)

77. Takei J, Itai S, Harada H, Furusawa Y, Miwa T, Fukui M, Nakamura T, Sano M, Sayama Y, Yanaka M, Handa S, Hisamatsu K, Nakamura Y, Yamada S, Kaneko MK, Kato Y.*
(*corresponding author)
Characterization of anti-goat podoplanin monoclonal antibody PMab-235 using immunohistochemistry against goat tissues.
Monoclon. Antib. Immunodiagn. Immunother., 38(5), 213–219, https://doi.org/10.1089/mab.2019.0022, 2019 (PDF)

76. Sajiki Y, Konnai S, Okagawa T, Nishimori A, Maekawa N, Goto S, Watari K, Minato E, Kobayashi A, Kohara J, Yamada S, Kaneko MK, Kato Y, Takahashi H, Terasaki N, Takeda A, Yamamoto K, Toda M, Suzuki Y, Murata S, Ohashi K.
Prostaglandin E2–Induced Immune Exhaustion and Enhancement of Antiviral Effects by Anti–PD-L1 Antibody Combined with COX-2 Inhibitor in Bovine Leukemia Virus Infection
J Immunol, 203(5):1313-1324, DOI: https://doi.org/10.4049/jimmunol.1900342, 2019 (PDF)

75. Nakano T, Ogasawara S, Tanaka T, Hozumi Y, Sano M, Sayama Y, Yamada S, Kaneko MK, Kato Y, Goto K.
DzMab-1: Anti-Human Diacylglycerol Kinase-zeta Monoclonal Antibody for Immunocytochemistry.
Monoclon. Antib. Immunodiagn. Immunother., 38(4), 179–182, doi: 10.1089/mab.2019.0020, 2019 (PDF)

74. Sano M, Kaneko MK, Kato Y.*.
(*corresponding author)
Epitope Mapping of Anti-Diacylglycerol Kinase Zeta Monoclonal Antibody DzMab-1 for Immunohistochemical Analyses.
Monoclon. Antib. Immunodiagn. Immunother., 38(4), 175–178, doi: 10.1089/mab.2019.0020, 2019 (PDF)

73. Takei J, Furusawa Y, Yamada S, Nakamura T, Sayama Y, Sano M, Konnai S, Kobayashi A, Harada H, Kaneko MK, Kato Y.*.
(*corresponding author)
PMab-247 Detects Bear Podoplanin in Immunohistochemical Analysis.
Monoclon. Antib. Immunodiagn. Immunother., 38(4), 171–174, https://doi.org/10.1089/mab.2019.0019, 2019 (PDF)

72. Kato Y*, Ohishi T, Yamada S, Itai S, Takei J, Sano M, Nakamura T, Harada H, Kawada M, Kaneko MK.
(*corresponding author)
Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody H2Mab-41 Exerts Antitumor Activity in a Mouse Xenograft Model of Colon Cancer.
Monoclon. Antib. Immunodiagn. Immunother., 38(4), 157–161; https://doi.org/10.1089/mab.2019.0017, 2019 (PDF)

71. Furusawa Y, Takei J, Sayama Y, Yamada S, Kaneko MK, Kato Y.*
(*corresponding author)
Development of an anti-bear podoplanin monoclonal antibody PMab-247 for immunohistochemical analysis
Biochem Biophys Rep., Volume 18, July 2019, 100644, https://doi.org/10.1016/j.bbrep.2019.100644, 2019 (PDF)

70. Kato Y*, Furusawa Y, Yamada S, Itai S, Takei J, Sano M, Kaneko MK.
(*corresponding author)
Establishment of a monoclonal antibody PMab-225 against alpaca podoplanin for immunohistochemical analyses
Biochem Biophys Rep., Volume 18, July 2019, 100633, https://authors.elsevier.com/sd/article/S2405580818303194, 2019 (PDF)

69. Furusawa Y, Yamada S, Itai S, Nakamura T, Takei J, Sano M, Harada H, Fukui M, Kaneko MK, Kato Y. *
(*corresponding author)
Establishment of a monoclonal antibody PMab-233 for immunohistochemical analysis against Tasmanian devil podoplanin
Biochem Biophys Rep., Volume 18, July 2019, 100631, https://doi.org/10.1016/j.bbrep.2019.100631 (PDF)

68. Furusawa Y, Yamada S, Nakamura T, Sano M, Sayama Y, Itai S, Takei J, Harada H, Fukui M, Kaneko MK, Kato Y.
PMab-235: a monoclonal antibody for immunohistochemical analysis against goat podoplanin
Heliyon, 5(7), e02063, 2019 (PDF)

67. Jangphattananont N, Sato H, Imamura R, Sakai K, Terakado Y, Murakami K, Barker N, Oshima H, Oshima M, Takagi J, Kato Y, Yano S, Matsumoto K.
Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach
Int. J. Mol. Sci.,20(12), 2955; https://doi.org/10.3390/ijms20122955, 2019 (PDF)

66. Kato Y*, Furusawa Y, Itai S, Takei J, Nakamura T, Sano M, Harada H, Yamada S, Kaneko MK.
(*corresponding author)
Establishment of an anti-cetacean podoplanin monoclonal antibody PMab-237 for immunohistochemical analysis
Monoclon. Antib. Immunodiagn. Immunother., 38(3), 108–113, https://doi.org/10.1089/mab.2019.0013, 2019 (PDF)

65. Yamada S, Itai S, Nakamura T, Takei J, Sano M, Konnai S, Kobayashi A, Nakagun S, Kobayashi Y, Kaneko MK, Kato Y.*
(*corresponding author)
Immunohistochemical analysis of the harbor porpoise using anti-podoplanin antibody PMab-237
Monoclon. Antib. Immunodiagn. Immunother., 38(3), 104–107, https://doi.org/10.1089/mab.2019.0014, 2019 (PDF)

64. Sano M, Kaneko MK, Kato Y.*.
(*corresponding author)
Epitope Mapping of Anti-Human DGKgamma Monoclonal Antibody DgMab-6
Monoclon. Antib. Immunodiagn. Immunother., 38(3), 120–123, https://doi.org/10.1089/mab.2019.0011, 2019 (PDF)

63. Kato Y*, Itai S, Yamada S, Suzuki H, Kaneko MK.
(*corresponding author)
Epitope Mapping of Anti-Diacylglycerol Kinase Zeta Monoclonal Antibody for the Detection of T cells by Immunohistochemical Analyses
Monoclon. Antib. Immunodiagn. Immunother., 38(3), 124–128, doi: 10.1089/mab.2019.0005., 2019 [Epub ahead of print](PDF)

62. Takei J, Itai S, Furusawa Y, Yamada S, Nakamura T, Sano M, Harada H, Fukui M, Kaneko MK, Kato Y*
(*corresponding author)
Epitope mapping of anti-tiger podoplanin monoclonal antibody PMab-231
Monoclon. Antib. Immunodiagn. Immunother., 38(3), 129–132, doi: 10.1089/mab.2019.0012., 2019 (PDF)

61. Kaneko MK, Yamada S, Itai S, Chang YW, Nakamura T, Yanaka M, Harada H, Suzuki H, Kato Y.*
(*corresponding author)
Elucidation of the TMab-6 Monoclonal Antibody Epitope Against Telomerase Reverse Transcriptase
Monoclon. Antib. Immunodiagn. Immunother., 38(3), 101–103, https://doi.org/10.1089/mab.2018.0007, 2019 (PDF)

60. Sakai K, Passioura T, Sato H, Ito K, Furuhashi H, Umitsu M, Takagi J, Kato Y, Mukai H, Warashina S, Zouda M, Watanabe Y, Yano S, Shibata M, Suga H, Matsumoto K.
Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor.
Nat Chem Biol., 15(6):598-606. doi: 10.1038/s41589-019-0285-7, 2019　(PDF)

59. Sudo H, Tsuji AB, Sugyo A, Saga T, Kaneko MK, Kato Y, Higashi T.
Therapeutic efficacy evaluation of radioimmunotherapy with 90Y-labeled anti-podoplanin antibody NZ-12 for mesothelioma
Cancer Sci., 110(5):1653-1664, https://doi.org/10.1111/cas.13979, 2019 (PDF)

58. Inoue M, Sakuta N, Watanabe S, Zhang Y, Yoshikaie K, Tanaka Y, Ushioda R, Kato Y, Takagi J, Tsukazaki T, Nagata K, Inaba K.
Structural Basis of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2b Regulation via Transmembrane Helix Interplay
Cell Rep., 27(4):1221-1230.e3. doi: 10.1016/j.celrep.2019.03.106., 2019 (PDF)

57. Kato Y*, Ohishi T, Yamada S, Itai S, Furusawa Y, Sano M, Nakamura T, Kawada M, Kaneko MK.
(*corresponding author)
Anti-CD133 monoclonal antibody CMab-43 exerts antitumor activity in a mouse xenograft model of colon cancer
Monoclon. Antib. Immunodiagn. Immunother., 38(2):75–78, https://doi.org/10.1089/mab.2019.0002, 2019 (PDF)

56. Furusawa Y, Kaneko MK, Nakamura T, Itai S, Fukui M, Harada H, Yamada S, Kato Y.*
(*corresponding author)
Establishment of a monoclonal antibody PMab-231 for tiger podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 38(2):89–95, https://doi.org/10.1089/mab.2019.0003, 2019 (PDF)

55. Kaneko MK, Furusawa Y, Sano M, Itai S, Takei J, Harada H, Fukui M, Yamada S, Kato Y.*
(*corresponding author)
Epitope mapping of the anti-horse podoplanin monoclonal antibody PMab-202
Monoclon. Antib. Immunodiagn. Immunother., 38(2):79–84, https://doi.org/10.1089/mab.2019.0001, 2019 (PDF)

54. Yamada S, Kaneko MK, Furusawa Y, Itai S, Sano M, Nakamura T, Yanaka M, Handa S, Hisamatsu K, Nakamura Y, Koyanagi M, Fukui M, Harada H, Kato Y.*
(*corresponding author)
Anti-bovine podoplanin monoclonal antibody PMab-44 detects goat podoplanin in immunohistochemistry
Monoclon. Antib. Immunodiagn. Immunother., 38(2):96–99, https://doi.org/10.1089/mab.2018.0031, 2019　(PDF)

53. Tamura R, Oi R, Akashi S, Kaneko MK, Kato Y, Nogi T
Application of the NZ-1 Fab as a crystallization chaperone for PA tag-inserted target proteins
Protein Sci. 28(4), 823-836, https://doi.org/10.1002/pro.3580, 2019 (PDF)

52. Kohei Kiname, Sho Yoshimoto, Daiki Kato, Masaya Tsuboi, Yuiko Tanaka, Ryohei Yoshitake, Shotaro Eto, Masahiro Shinada, James Chambers, Kohei Saeki, Ryohei Kinoshita, Shinji Yamada, Kazuyuki Uchida, Mika K. Kaneko, Ryohei Nishimura, Yukinari Kato, Takayuki Nakagawa
Evaluation of immunohistochemical staining with PMab-38, an anti-dog podoplanin monoclonal antibody, in various canine tumor tissues
Japanese Journal of Veterinary Research, 67(1); 25-34, 2019 (PDF)

51. Furusawa Y, Yamada S, Itai S, Sano M, Nakamura T, Yanaka M, Fukui M, Harada H, Mizuno T, Sakai Y, Takasu M, Kaneko MK, Kato Y*.
(*corresponding author)
PMab-210: A Monoclonal Antibody Against Pig Podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 38(1), 30-36; https://doi.org/10.1089/mab.2018.0038, 2019 (PDF)

50. Sano M, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope Mapping of Anti-Diacylglycerol Kinase alpha Monoclonal Antibody DaMab-2
Monoclon. Antib. Immunodiagn. Immunother., 38(1), 8-11; https://doi.org/10.1089/mab.2018.0047, 2019 (PDF)

49. Kato Y*, Yamada S, Furusawa Y, Itai S, Nakamura T, Yanaka M, Sano M, Harada H, Fukui M, Kaneko MK.
(*corresponding author)
PMab-213: a monoclonal antibody for immunohistochemical analysis against pig podoplanin
Monoclon. Antib. Immunodiagn. Immunother., 38(1), 18-24; https://doi.org/10.1089/mab.2018.0048, 2019 (PDF)

48. Furusawa Y, Yamada S, Itai S, Nakamura T, Yanaka M, Sano M, Harada H, Fukui M, Kaneko MK, Kato Y.*
(*corresponding author)
PMab-219: a monoclonal antibody for the immunohistochemical analysis of horse podoplanin
Biochem Biophys Rep., 18:100616. doi: 10.1016/j.bbrep.2019.01.009., 2019 (PDF)

47. Kato Y*, Ohishi T, Kawada M, Maekawa N, Konnai S, Itai S, Yamada S, Kaneko MK.
(*corresponding author)
The mouse–canine chimeric anti-dog podoplanin antibody P38B exerts antitumor activity in mouse xenograft models
Biochem Biophys Rep., 17:23–26, 2019 (PDF)

2018

46. Yamada S, Itai S, Kaneko MK, Kato Y*.
(*corresponding author)
PMab-48 recognizes canine podoplanin of lymphatic endothelial cells.
Monoclon. Antib. Immunodiagn. Immunother., 37(1): 63-66, 2018 (PDF)

45. Kato Y*, Yamada S, Itai S, Kobayashi A, Konnai S, Kaneko MK.
(*corresponding author)
Anti-Horse Podoplanin Monoclonal Antibody PMab-219 is useful for detecting lymphatic endothelial cells by immunohistochemical analysis
Monoclon. Antib. Immunodiagn. Immunother., 37(6); 272–274, https://doi.org/10.1089/mab.2018.0044, 2018　(PDF)

44. Kato Y*, Yamada S, Itai S, Konnai S, Kobayashi A, Kaneko MK.
(*corresponding author)
Detection of alpaca podoplanin by immunohistochemistry using the anti-bovine podoplanin monoclonal antibody PMab-44
Monoclon. Antib. Immunodiagn. Immunother., 37(6); 269–271, doi: 10.1089/mab.2018.0037, 2018 (PDF)

43. Kato Y*, Yamada S, Itai S, Kobayashi A, Konnai S, Kaneko MK.
(*corresponding author)
Immunohistochemical detection of sheep podoplanin using an anti-bovine podoplanin monoclonal antibody PMab-44
Monoclon. Antib. Immunodiagn. Immunother., 37(6); 265–268, doi: 10.1089/mab.2018.0036., 2018 (PDF)

42. Sajiki Y, Konnai S, Okagawa T, Nishimori A, Maekawa N, Goto S, Ikebuchi R, Nagata R, Kawaji S, Kagawa Y, Yamada S, Kato Y, Nakajima C, Suzuki Y, Murata S, Mori Y, Ohashi K.
Prostaglandin E2 induction suppresses the Th1 immune responses in cattle with Johne's disease.
Infect Immun., 86(5)., pii: IAI.00910-17. doi: 10.1128/IAI.00910-17., 2018 (PDF）

41. Kato Y*, Mizuno T, Yamada S, Nakamura T, Itai S, Yanaka M, Sano M, Kaneko MK.
(*corresponding author)
Establishment of P38Bf, a Core-Fucose-Deficient Mouse-Canine Chimeric Antibody against Dog Podoplanin
Monoclon. Antib. Immunodiagn. Immunother.,37(5):218–223, https://doi.org/10.1089/mab.2018.0035, 2018　(PDF)

40. Yamada S, Itai S, Furusawa Y, Sano M, Nakamura T, Yanaka M, Handa S, Hisamatsu K, Nakamura Y, Fukui M, Harada H, Mizuno T, Sakai Y, Ogasawara S, Murata T, Uchida H, Tahara H, Kaneko MK, Kato Y.*
(*corresponding author)
Detection of tiger podoplanin using the anti-cat podoplanin monoclonal antibody PMab-52
Monoclon. Antib. Immunodiagn. Immunother.,37(5):224–228, https://doi.org/10.1089/mab.2018.0033, 2018　(PDF)

39. Furusawa Y, Yamada S, Itai S, Sano M, Nakamura T, Yanaka M, Handa S, Mizuno T, Maeda K, Fukui M, Harada H, Kaneko MK, Kato Y.*
(*corresponding author)
Establishment of Monoclonal Antibody PMab-202 against Horse Podoplanin
Monoclon. Antib. Immunodiagn. Immunother.,37(5):233–237, https://doi.org/10.1089/mab.2018.0030, 2018　(PDF)

38. Nakano T, Ogasawara S, Tanaka T, Hozumi Y, Yamaki A, Sakane F, Shirai Y, Nakamura T, Yanaka M, Yamada S, Kaneko MK, Kato Y, Goto K.
DgMab-6: Anti-Human DGKgamma Monoclonal Antibody for immunocytochemistry
Monoclon. Antib. Immunodiagn. Immunother.,37(5):233–237, https://doi.org/10.1089/mab.2018.0026, 2018　(PDF)

37. Itai S, Yamada S, Kaneko MK, Sano M, Nakamura T, Yanaka M, Handa S, Hisamatsu K, Nakamura Y, Furusawa Y, Fukui M, Ohishi T, Kawada M, Harada H, Kato Y.*.
(*corresponding author)
Podocalyxin is crucial for the growth of oral squamous cell carcinoma cell line HSC-2
Biochem Biophys Rep., 15: 93-96, https://doi.org/10.1016/j.bbrep.2018.07.008, 2018　(PDF)

36. Furusawa Y, Yamada S, Itai S, Nakamura T, Fukui M, Harada H, Kaneko MK, Kato Y.*
(*corresponding author)
Elucidation of critical epitope of anti-rat podoplanin monoclonal antibody PMab-2
Monoclon. Antib. Immunodiagn. Immunother., 37(4): 188–193, https://doi.org/10.1089/mab.2018.0025, 2018 (PDF)

35. Kaneko MK, Yamada S, Itai S, Furusawa Y, Nakamura T, Yanaka M, Handa S, Hisamatsu K, Nakamura Y, Fukui M, Harada H, Kato Y*.
(*corresponding author)
Epitope mapping of an anti-alpha thalassemia/mental retardation syndrome X-linked monoclonal antibody AMab-6
Biochem Biophys Rep.,15: 76-80, https://doi.org/10.1016/j.bbrep.2018.07.003, 2018 (PDF)

34. Yamada S, Itai S, Kaneko MK, Konnai S, Kato Y*.
(*corresponding author)
Epitope mapping of anti-mouse podoplanin monoclonal antibody PMab-1
Biochem Biophys Rep., 15:52-56, https://doi.org/10.1016/j.bbrep.2018.07.002, 2018 (PDF)

33. Furusawa Y, Itai S, Yamada S, Kaneko MK, Kato Y.*
(*corresponding author)
Epitope mapping of anti-telomerase reverse transcriptase (TERT) monoclonal antibodies
Monoclon. Antib. Immunodiagn. Immunother., 37(4): 185–187, https://doi.org/10.1089/mab.2018.0019, 2018 (PDF)

32. Okagawa T, Konnai S, Nishimori A, Maekawa N, Goto S, Ikebuchi R, Kohara J, Suzuki Y, Yamada S, Kato Y, Murata S, Ohashi K.
Cooperation of PD-1 and LAG-3 in the exhaustion of CD4+ and CD8+ T cells during bovine leukemia virus infection
Vet Res.,49(1):50. doi: 10.1186/s13567-018-0543-9., 2018 (PDF)

31. Itai S, Yamada S, Kaneko MK, Kato Y*.
(*corresponding author)
Determination of critical epitope of PcMab-47 against human podocalyxin
Biochem Biophys Rep.,14: 78–82, https://doi.org/10.1016/j.bbrep.2018.04.003, 2018 (PDF)

30. Kaneko MK, Yamada S, Itai S, Chang YW, Nakamura T, Yanaka M, Kato Y*.
(*corresponding author)
Elucidation of the critical epitope of an anti-EGFR monoclonal antibody EMab-134
Biochem Biophys Rep., 14, 54-57, 2018 (PDF)

29. Yamada Y, Itai S, Nakamura T, Yanaka M, Kaneko MK, Kato Y*.
(*corresponding author)
Detection of high CD44 expression in oral cancers using the novel monoclonal antibody, C44Mab-5
Biochem Biophys Rep.,14, 64-68, 2018 (PDF)

28. Retzbach EP, Sheehan SA, Nevel E, Batra A, Phi T, Kato Y, Baredes S, Fatahzadeh M, Shienbaum AJ, and Goldberg GS.
Podoplanin emerges as a functionally relevant oral cancer biomarker and therapeutic target.
Oral Oncology, 78, 126–136, 2018 (PDF)

27. Itai S, Ohishi T, Kaneko MK, Yamada S, Abe S, Nakamura T, Yanaka M, Chang YW, Ohba SI, Nishioka Y, Kawada M, Harada H, Kato Y*.
(*corresponding author)
Anti-podocalyxin antibody exerts antitumor effects via antibody-dependent cellular cytotoxicity in mouse xenograft models of oral squamous cell carcinoma.
Oncotarget, 9(32):22480-22497, https://doi.org/10.18632/oncotarget.25132, 2018 (PDF)

26. Tabata S, Kitago Y, Fujii Y, Mihara E, Tamura-Kawakami K, Norioka N, Takahashi K, Kaneko MK, Kato Y, Takagi J.
An anti-peptide monoclonal antibody recognizing the tobacco etch virus protease-cleavage sequence and its application to a tandem tagging system.
Protein Expr Purif., 147, 94-99, doi: 10.1016/j.pep.2018.03.004, 2018 (PDF)

25. Kaneko MK, Itai S, Yamada S, Kato Y*.
(*corresponding author)
47-mG2a: A Mouse IgG2a-type of PcMab-47 Useful for Detecting Podocalyxin in Esophageal Cancers by Immunohistochemistry
Monoclon. Antib. Immunodiagn. Immunother., 37(3),158–161, doi: 10.1089/mab.2018.0003., 2018 (PDF)

24. Miyazaki A, Nakai H, Sonoda T, Hirohashi Y, Kaneko MK, Kato Y, Sawa Y, Hiratsuka H.
LpMab-23-recognizing cancer-type podoplanin is a novel predictor for a poor prognosis of oral cancer.
Oncotarget,9(30):21156-21165. https://doi.org/10.18632/oncotarget.24986, 2018 (PDF)

23. Yamada S, Itai S, Nakamura T, Yanaka M, Chang YW, Suzuki H, Kaneko MK, Kato Y.*.
(*corresponding author)
Monoclonal Antibody L1Mab-13 Detected PD-L1 in Lung Cancers.
Monoclon. Antib. Immunodiagn. Immunother., 110-115, doi: 10.1089/mab.2018.0004, 37(2), 2018 (PDF)

22. Yamada S, Kaneko MK, Itai S, Chang YW, Nakamura T, Yanaka M, Ogasawara S, Murata T, Uchida H, Tahara H, Harada H, Kato Y.*.
(*corresponding author)
Epitope Mapping of Monoclonal Antibody PMab-48 against Dog Podoplanin.
Monoclon. Antib. Immunodiagn. Immunother., 37(3),162–165, doi: 10.1089/mab.2018.0006, 2018 (PDF)

21. Yamamichi A, Ohka F, Aoki K, Suzuki H, Kato A, Hirano M, Motomura K, Tanahashi K, Chalise L, Maeda S, Wakabayashi T, Kato Y, Natsume A.
Immunohistochemical ATRX loss cannot be a surrogate for 1p19q codeletion.
Brain Tumor Pathol., 35(2):106-113, doi: 10.1007/s10014-018-0312-5., 2018 (PDF)

20. Ito A, Ohta M, Kato Y, Inada S, Kato T, Nakata S, Yatabe Y, Goto M, Kaneda N, Kurita K, Nakanishi H, Yoshida K.
A real time near-infrared imaging method for the detection of oral cancers in mice using an indocyanine green-labeled podoplanin antibody.
Technol Cancer Res Treat., 17:1533033818767936. doi: 10.1177/1533033818767936., 2018 (PDF）

19. Yamada S, Itai S, Kaneko MK, Kato Y*.
(*corresponding author)
Anti-Podocalyxin Monoclonal Antibody 47-mG2a Detects Lung Cancers by Immunohistochemistry Analyses.
Monoclon. Antib. Immunodiagn. Immunother., 37(2), https://doi.org/10.1089/mab.2018.0002, 91-94, 2018 (PDF)

18. Yamada S, Itai S, Kaneko MK, Kato Y*.
(*corresponding author)
Detection of high PD-L1 expression in oral cancers by a novel monoclonal antibody L1Mab-4
Biochem Biophys Rep., 13, 123–128, 2018 (PDF)

17. Masui K, Komori T, Kato Y, Masutomi K, Ichimura K, Ogasawara S, Kaneko MK, Oki H, Suzuki H, Nitta M, Maruyama T, Muragaki Y, Kawamata T, Sawada T, Shibata N.
Elevated TERT Expression in TERT Wild-Type Adult Diffuse Gliomas: Histological Evaluation with a Novel TERT-Specific Antibody
Biomed Res Int.:7945845. doi: 10.1155/2018/7945845., 2018 (PDF)

16. Chang YW, Kaneko MK, Yamada S, Kato Y.*
(*corresponding author)
Epitope Mapping of Monoclonal Antibody PMab-52 Against Cat Podoplanin.
Monoclon. Antib. Immunodiagn. Immunother., 37(2): 95–99, https://doi.org/10.1089/mab.2017.0067, 2018 (PDF)

15. Kaneko MK, Yamada, S, Itai S, Kato Y*.
(*corresponding author)
Development of an Anti-HER2 Monoclonal Antibody (H2Mab-139) Against Colon Cancer.
Monoclon. Antib. Immunodiagn. Immunother., 37(1): 59-62, 2018 (PDF)

14. Suzuki T, Takakubo Y, Oki H, Liu X, Honma R, Naganuma Y, Goodman S, Kaneko MK, Kato Y, Takagi M.
Immunohistochemical Analysis of Inflammatory Rheumatoid Synovial Tissues Using Anti-Human Podoplanin Monoclonal Antibody Panel.
Monoclon. Antib. Immunodiagn. Immunother., 37(1): 12-19, 2018 (PDF)



2017

13. Nuemket N, Yasui N, Kusakabe Y, Nomura Y, Atsumi N, Akiyama S, Nango E, Kato Y, Kaneko MK, Takagi J, Hosotani M, Yamashita A.
Structural basis for perception of diverse chemical substances by T1r taste receptors.
Open Access
Nature Communications, 23;8:15530, 2017 (PDF)

12. Yamada S, Itai S, Nakamura T, Chang YW, Harada H, Suzuki H, Kaneko MK, Kato Y*.
(*corresponding author)
Establishment of H2Mab-119, an Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody, Against Pancreatic Cancer.
Monoclon. Antib. Immunodiagn. Immunother.,36(6): 287-290, 2017 (PDF)

11. Chang YW, Yamada S, Kaneko MK, Kato Y*.
(*corresponding author)
Epitope Mapping of Monoclonal Antibody PMab-38 Against Dog Podoplanin.
Monoclon. Antib. Immunodiagn. Immunother., 36(6): 291-295, 2017 (PDF)

10. Tamahara T, Ochiai K, Muto A, Kato Y, Sax N, Matsumoto M, Koseki T, Igarashi K.
mTOR-Bach2 cascade controls cell cycle and class switch recombination during B cell differentiation.
Mol Cell Biol., 37(24)., doi: 10.1128/MCB.00418-17., 2017

9. Itai S, Yamada S, Kaneko MK, Harada H, Kagawa Y, Konnai S, Kato Y*.
(*corresponding author)
Expression of cat podoplanin in feline squamous cell carcinomas.
Monoclon. Antib. Immunodiagn. Immunother.,36(6): 243-250, 2017 (PDF)

8. Itai S, Yamada S, Kaneko MK, Chang YW, Harada, H, Kato Y*.
(*corresponding author)
Establishment of EMab-134, a sensitive and specific anti-epidermal growth factor receptor monoclonal antibody for detecting squamous cell carcinoma cells of the oral cavity.
Monoclon. Antib. Immunodiagn. Immunother., 36(6): 272-281, 2017 (PDF)

7. Maekawa N, Konnai S, Takagi S, Kagawa Y, Okagawa T, Nishimori A, Ikebuchi R, Izumi Y, Deguchi T, Nakajima C, Kato Y, Yamamoto K, Uemura H, Suzuki Y, Murata S, Ohashi K.
A canine chimeric monoclonal antibody targeting PD-L1 and its clinical efficacy in canine oral malignant melanoma or undifferentiated sarcoma.
Sci Rep. ,7(1):8951. doi: 10.1038/s41598-017-09444-2, 2017

6. Itai S, Fujii Y, Nakamura T, Chang YW, Yanaka M, Saidoh N, Handa S, Suzuki H, Harada H, Yamada S, Kaneko MK, Kato Y*.
(*corresponding author)
Establishment of CMab-43, a Sensitive and Specific Anti-CD133 Monoclonal Antibody, for Immunohistochemistry.
Monoclon. Antib. Immunodiagn. Immunother., 36(5):231-235, 2017

5. Itai S, Kaneko MK, Fujii Y, Yamada S, Nakamura T, Yanaka M, Saidoh N, Handa S, Chang Yao-Wen, Suzuki H, Harada H, Kato Y.
(*corresponding author)
Development of EMab-51, a Sensitive and Specific Anti-EGFR Monoclonal Antibody in Western Blot and Immunohistochemistry.
Monoclon. Antib. Immunodiagn. Immunother., 36(5):214-219, 2017

4. Itai S, Yamada S, Kaneko MK, Harada H, Kato Y.
(*corresponding author)
Immunohistochemical Analysis Using Anti-Podocalyxin Monoclonal Antibody PcMab-47 Demonstrates Podocalyxin Expression in Oral Squamous Cell Carcinoma Cells.
Monoclon. Antib. Immunodiagn. Immunother., 36(5):220-223, 2017

3. Yamada S, Itai S, Nakamura T, Yanaka M, Saidoh N, Chang YW, Handa S, Harada H, Kagawa Y, Ichii O, Konnai S, Kaneko MK, Kato Y.
PMab-52: Specific and Sensitive Monoclonal Antibody against Cat Podoplanin for Immunohistochemistry.
Monoclon. Antib. Immunodiagn. Immunother., 36(5):224-230, 2017

2. Itai S, Fujii Y, Kaneko MK, Yamada S, Nakamura T, Yanaka M, Saidoh N, Chang YW, Handa S, Takahashi M, Suzuki H, Harada H, Kato Y.
H2Mab-77 is a sensitive and specific anti-HER2 monoclonal antibody against breast cancer.
Monoclon. Antib. Immunodiagn. Immunother., 36(4): 143-148, 2017

1. Kaneko MK, Kunita A, Yamada S, Nakamura T, Yanaka M, Saidoh N, Chang YW, Handa S, Ogasawara S, Ohishi T, Abe S, Itai S, Harada H, Kawada M, Nishioka Y, Fukayama M, Kato Y.*
Anti-Podocalyxin Antibody chPcMab-47 Exerts Antitumor Activity in Mouse Xenograft Models of Colorectal Adenocarcinomas.
Monoclon. Antib. Immunodiagn. Immunother., 36(4): 157-162, 2017